@inproceedings{ac650ad767af4172a822378c8846fcf0,
title = "In situ quantification of local O 2 concentration in 3D bioprinted constructs using luminescent nanoparticles",
abstract = " One major limitation of tissue engineering approaches is the insufficient supply of the cells with oxygen due to a lack of a functional vascular system ex vivo. In complex 3D culture systems, such as bioprinted constructs with clinically relevant dimensions (Kilian D. MRS Bull. 2017; 42: 582-592), the local O 2 concentration depends on the macroporosity of the hydrogel scaffold as well as on the permeability of the hydrogel material (bioink) which oxygen has to pass through via diffusion. For better understanding new tools are needed to monitor in real time oxygen distribution dynamics within bioprinted constructs. We propose utilisation of cytocompatible O 2 sensitive luminescent nanoparticles (NP) for this purpose. ",
author = "Akkineni, {A. R.} and E. Trampe and K. Koren and A. Lode and F. Krujatz and M. K{\"u}hl and Michael Gelinsky",
year = "2019",
month = jan,
day = "1",
language = "English",
series = "Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium",
publisher = "Wiley, Periodics, Society for Biomaterials",
booktitle = "Society for Biomaterials Annual Meeting and Exposition 2019",
note = "42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence ; Conference date: 03-04-2019 Through 06-04-2019",
}