Impaired awareness of deficits and neuropsychiatric symptoms in early Alzheimer's disease: the Danish Alzheimer Intervention Study (DAISY)

A. Vogel; Frans Boch Waldorff; G. Waldemar; Asmus Vogel; Frans Boch Waldorff; Gunhild Waldemar

doi:10.1176/appi.neuropsych.22.1.93

Impaired awareness of deficits and neuropsychiatric symptoms in early Alzheimer's disease: the Danish Alzheimer Intervention Study (DAISY)

A. Vogel, Frans Boch Waldorff, G. Waldemar, Asmus Vogel, Frans Boch Waldorff, Gunhild Waldemar

28 Citations (Scopus)

Abstract

Impaired awareness may be associated with increased neuropsychiatric symptoms in moderate to severe Alzheimer's disease, but relatively little is known about the association in early Alzheimer's disease. The aim of this study was to investigate if impaired awareness was associated with a higher frequency of neuropsychiatric symptoms in early Alzheimer's disease. In a Danish multicenter study, 321 patients with MMSE score ≥20 were evaluated. Patients with poor insight had significantly more neuropsychiatric symptoms than patients with full insight. When patients had increasing neuropsychiatric symptoms, caregivers reported higher levels of distress.

Original language	English
Journal	Journal of Neuropsychiatry and Clinical Neurosciences
Volume	22
Issue number	1
Pages (from-to)	93-9
Number of pages	7
ISSN	0895-0172
DOIs	https://doi.org/10.1176/appi.neuropsych.22.1.93
Publication status	Published - 1 Jan 2010

Access to Document

10.1176/appi.neuropsych.22.1.93

Cite this

Impaired awareness of deficits and neuropsychiatric symptoms in early Alzheimer's disease: the Danish Alzheimer Intervention Study (DAISY). / Vogel, A.; Waldorff, Frans Boch ; Waldemar, G. et al.

In: Journal of Neuropsychiatry and Clinical Neurosciences, Vol. 22, No. 1, 01.01.2010, p. 93-9.

Research output: Contribution to journal › Journal article › Research › peer-review

@article{c1c70a706a4c11df928f000ea68e967b,

title = "Impaired awareness of deficits and neuropsychiatric symptoms in early Alzheimer's disease: the Danish Alzheimer Intervention Study (DAISY)",

abstract = "Impaired awareness may be associated with increased neuropsychiatric symptoms in moderate to severe Alzheimer's disease, but relatively little is known about the association in early Alzheimer's disease. The aim of this study was to investigate if impaired awareness was associated with a higher frequency of neuropsychiatric symptoms in early Alzheimer's disease. In a Danish multicenter study, 321 patients with MMSE score ≥20 were evaluated. Patients with poor insight had significantly more neuropsychiatric symptoms than patients with full insight. When patients had increasing neuropsychiatric symptoms, caregivers reported higher levels of distress.",

author = "A. Vogel and Waldorff, {Frans Boch} and G. Waldemar and Asmus Vogel and Waldorff, {Frans Boch} and Gunhild Waldemar",

note = "DA - 20100217IS - 1545-7222 (Electronic)IS - 0895-0172 (Linking)LA - engPT - Journal ArticlePT - Research Support, Non-U.S. Gov'tSB - IM",

year = "2010",

month = jan,

day = "1",

doi = "10.1176/appi.neuropsych.22.1.93",

language = "English",

volume = "22",

pages = "93--9",

journal = "Journal of Neuropsychiatry and Clinical Neurosciences",

issn = "0895-0172",

publisher = "American Psychiatric Publishing, Inc.",

number = "1",

}

TY - JOUR

T1 - Impaired awareness of deficits and neuropsychiatric symptoms in early Alzheimer's disease: the Danish Alzheimer Intervention Study (DAISY)

AU - Vogel, A.

AU - Waldorff, Frans Boch

AU - Waldemar, G.

AU - Vogel, Asmus

AU - Waldorff, Frans Boch

AU - Waldemar, Gunhild

N1 - DA - 20100217IS - 1545-7222 (Electronic)IS - 0895-0172 (Linking)LA - engPT - Journal ArticlePT - Research Support, Non-U.S. Gov'tSB - IM

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Impaired awareness may be associated with increased neuropsychiatric symptoms in moderate to severe Alzheimer's disease, but relatively little is known about the association in early Alzheimer's disease. The aim of this study was to investigate if impaired awareness was associated with a higher frequency of neuropsychiatric symptoms in early Alzheimer's disease. In a Danish multicenter study, 321 patients with MMSE score ≥20 were evaluated. Patients with poor insight had significantly more neuropsychiatric symptoms than patients with full insight. When patients had increasing neuropsychiatric symptoms, caregivers reported higher levels of distress.

AB - Impaired awareness may be associated with increased neuropsychiatric symptoms in moderate to severe Alzheimer's disease, but relatively little is known about the association in early Alzheimer's disease. The aim of this study was to investigate if impaired awareness was associated with a higher frequency of neuropsychiatric symptoms in early Alzheimer's disease. In a Danish multicenter study, 321 patients with MMSE score ≥20 were evaluated. Patients with poor insight had significantly more neuropsychiatric symptoms than patients with full insight. When patients had increasing neuropsychiatric symptoms, caregivers reported higher levels of distress.

U2 - 10.1176/appi.neuropsych.22.1.93

DO - 10.1176/appi.neuropsych.22.1.93

M3 - Journal article

SN - 0895-0172

VL - 22

SP - 93

EP - 99

JO - Journal of Neuropsychiatry and Clinical Neurosciences

JF - Journal of Neuropsychiatry and Clinical Neurosciences

IS - 1

ER -

Impaired awareness of deficits and neuropsychiatric symptoms in early Alzheimer's disease: the Danish Alzheimer Intervention Study (DAISY)

Abstract

Access to Document

Fingerprint

Cite this