IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC

Claus Selch Larsen; Susan Weng Larsen; Mette Agergaard Thing; Jesper Langgaard Kristensen; HENRIK JENSEN,; JESPER ØSTERGAARD,

IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC

Claus Selch Larsen (Inventor), Susan Weng Larsen (Inventor), Mette Agergaard Thing (Inventor), Jesper Langgaard Kristensen (Inventor), HENRIK JENSEN, (Inventor), JESPER ØSTERGAARD, (Inventor)

Abstract

The present invention relates to a compound of formula (I): wherein R1is R3-IPU and R2 is the acyloxy residue of diclofenac, and specified by the following structures: (II), (III) wherein OH-R3-IPU is selected from (IV) and R4 and R5 may be the same or different selected from H and CH3 and salts, solvates and hydrates thereof. The compounds are used for the treatment of pain such as postoperative pain following arthroscopic surgery.

Original language	English
IPC	A61P 29/ 00 A I
Patent number	WO2016066612
Country/Territory	Denmark
Priority date	28/10/2014
Priority number	DK20140070657
Publication status	Published - 6 May 2016

Cite this

@misc{74c85c6a18d7465aace47bd4d6528960,

title = "IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC",

abstract = "The present invention relates to a compound of formula (I): wherein R1is R3-IPU and R2 is the acyloxy residue of diclofenac, and specified by the following structures: (II), (III) wherein OH-R3-IPU is selected from (IV) and R4 and R5 may be the same or different selected from H and CH3 and salts, solvates and hydrates thereof. The compounds are used for the treatment of pain such as postoperative pain following arthroscopic surgery.",

author = "Larsen, {Claus Selch} and Larsen, {Susan Weng} and Thing, {Mette Agergaard} and Kristensen, {Jesper Langgaard} and HENRIK JENSEN, and JESPER {\O}STERGAARD,",

year = "2016",

month = may,

day = "6",

language = "English",

type = "Patent",

note = "WO2016066612; A61P 29/ 00 A I",

}

TY - PAT

T1 - IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC

AU - Larsen, Claus Selch

AU - Larsen, Susan Weng

AU - Thing, Mette Agergaard

AU - Kristensen, Jesper Langgaard

AU - JENSEN,, HENRIK

AU - ØSTERGAARD,, JESPER

PY - 2016/5/6

Y1 - 2016/5/6

N2 - The present invention relates to a compound of formula (I): wherein R1is R3-IPU and R2 is the acyloxy residue of diclofenac, and specified by the following structures: (II), (III) wherein OH-R3-IPU is selected from (IV) and R4 and R5 may be the same or different selected from H and CH3 and salts, solvates and hydrates thereof. The compounds are used for the treatment of pain such as postoperative pain following arthroscopic surgery.

AB - The present invention relates to a compound of formula (I): wherein R1is R3-IPU and R2 is the acyloxy residue of diclofenac, and specified by the following structures: (II), (III) wherein OH-R3-IPU is selected from (IV) and R4 and R5 may be the same or different selected from H and CH3 and salts, solvates and hydrates thereof. The compounds are used for the treatment of pain such as postoperative pain following arthroscopic surgery.

M3 - Patent

M1 - WO2016066612

ER -

IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC

Abstract

Fingerprint

Cite this