Imaging of insulin signaling in skeletal muscle of living mice shows major role of T-tubules.

Biochemistry, Genetics and Molecular Biology

• Skeletal Muscle 100%
• Insulin Signaling 100%
• Sarcolemma 100%
• T-Tubule 100%
• GLUT4 100%
• Phosphatidylinositol 75%
• Dynamics 50%
• Facilitated Diffusion 50%
• Glucose Transport 50%
• Insulin Receptor 25%
• Green Fluorescent Protein 25%
• Confocal Microscopy 25%
• Membrane Invagination 25%
• Immunostaining 25%
• Glucose Transporter 25%
• Insulin Resistance 25%

Medicine and Dentistry

• Glucose Transporter 4 100%
• Insulin Signaling 100%
• Sarcolemma 100%
• Transverse Tubular System 100%
• Skeletal Muscle 100%
• Phosphatidylinositol 75%
• Glucose Uptake 50%
• Maturity Onset Diabetes of the Young 25%
• Fluorescent Dye 25%
• Green Fluorescent Protein 25%
• Insulin Resistance 25%
• Insulin Receptor 25%
• Imaging Technique 25%
• Intravenous Drug Administration 25%
• Confocal Microscopy 25%
• Membrane Invagination 25%
• Immunohistochemistry 25%

Keyphrases

• Aged Mice 100%
• Insulin Signaling 100%
• Skeletal muscle 100%
• T-tubules 100%
• Sarcolemma 44%
• Insulin 44%
• GLUT4 Translocation 33%
• Phosphatidylinositol 3 33%
• Muscle Fiber 22%
• Insulin Receptor 11%
• Early Events 11%
• Type 2 Diabetes Mellitus (T2DM) 11%
• Membrane Invagination 11%
• Immunostaining 11%
• Green Fluorescent Protein 11%
• Glucose Transport 11%
• Labeled Protein 11%
• Temporal Distribution 11%
• Glucose Transporter 1 (GLUT1) 11%
• Living Animals 11%
• Glucose Transporter 4 (GLUT4) 11%
• Muscle Glucose Uptake 11%
• Fluorescent Dye 11%
• Intravenous Injection 11%
• Insulin Resistance 11%
• Confocal Imaging 11%
• Spatial Distribution 11%
• Imaging Techniques 11%
• Insulin Action 11%
• In Situ 11%