Image dissimilarity-based quantification of lung disease from CT

Lauge Sørensen, Marco Loog, Pechin Chien Pau Lo, Haseem Ashraf, Asger Dirksen, Robert P. W. Duin, Marleen de Bruijne

18 Citations (Scopus)

Abstract

In this paper, we propose to classify medical images using dissimilarities computed between collections of regions of interest. The images are mapped into a dissimilarity space using an image dissimilarity measure, and a standard vector space-based classifier is applied in this space. The classification output of this approach can be used in computer aided-diagnosis problems where the goal is to detect the presence of abnormal regions or to quantify the extent or severity of abnormalities in these regions. The proposed approach is applied to quantify chronic obstructive pulmonary disease in computed tomography (CT) images, achieving an area under the receiver operating characteristic curve of 0.817. This is significantly better compared to combining individual region classifications into an overall image classification, and compared to common computerized quantitative measures in pulmonary CT.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - MICCAI 2010 : 13th International Conference, Beijing, China, September 20-24, 2010, Proceedings, Part I
EditorsTianzi Jiang, Nassir Navab, Josien P. W. Pluim, Max A. Viergever
Number of pages8
VolumePart I
PublisherSpringer
Publication date2010
Pages37-44
ISBN (Print)978-3-642-15704-2
ISBN (Electronic)978-3-642-15705-9
DOIs
Publication statusPublished - 2010
Event13th International Conference on Medical Image Computing and Computer Assisted Intervention - Beijing, China
Duration: 20 Sept 201024 Sept 2010
Conference number: 13

Conference

Conference13th International Conference on Medical Image Computing and Computer Assisted Intervention
Number13
Country/TerritoryChina
CityBeijing
Period20/09/201024/09/2010
SeriesLecture notes in computer science
Number6361
ISSN0302-9743

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