Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI

Sune H Keller; Søren Holm; Adam E Hansen; Bernhard Sattler; Flemming Andersen; Thomas L Klausen; Liselotte Højgaard; Andreas Kjær; Thomas Beyer

doi:10.1007/s10334-012-0345-4

Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI

Sune H Keller, Søren Holm, Adam E Hansen, Bernhard Sattler, Flemming Andersen, Thomas L Klausen, Liselotte Højgaard, Andreas Kjær, Thomas Beyer

100 Citations (Scopus)

Abstract

Purpose: Integrated whole-body PET/MRI tomographs have become available. PET/MR imaging has the potential to supplement, or even replace combined PET/CT imaging in selected clinical indications. However, this is true only if methodological pitfalls and image artifacts arising from novel MR-based attenuation correction (MR-AC) are fully understood. Results: Here we present PET/MR image artifacts following routine MR-AC, as most frequently observed in clinical operations of an integrated whole-body PET/MRI system. Conclusion: A clinical adoption of integrated PET/MRI should entail the joint image display and interpretation of MR data, MR-based attenuation maps and uncorrected plus attenuation-corrected PET images in order to recognize potential pitfalls from MR-AC and to ensure clinically accurate image interpretation.

Original language	English
Journal	Magnetic Resonance Materials in Physics, Biology and Medicine
Volume	26
Issue number	1
Pages (from-to)	173-81
Number of pages	9
ISSN	0968-5243
DOIs	https://doi.org/10.1007/s10334-012-0345-4
Publication status	Published - Feb 2013

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title = "Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI",

abstract = "Purpose: Integrated whole-body PET/MRI tomographs have become available. PET/MR imaging has the potential to supplement, or even replace combined PET/CT imaging in selected clinical indications. However, this is true only if methodological pitfalls and image artifacts arising from novel MR-based attenuation correction (MR-AC) are fully understood. Results: Here we present PET/MR image artifacts following routine MR-AC, as most frequently observed in clinical operations of an integrated whole-body PET/MRI system. Conclusion: A clinical adoption of integrated PET/MRI should entail the joint image display and interpretation of MR data, MR-based attenuation maps and uncorrected plus attenuation-corrected PET images in order to recognize potential pitfalls from MR-AC and to ensure clinically accurate image interpretation.",

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T1 - Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI

AU - Keller, Sune H

AU - Holm, Søren

AU - Hansen, Adam E

AU - Sattler, Bernhard

AU - Andersen, Flemming

AU - Klausen, Thomas L

AU - Højgaard, Liselotte

AU - Kjær, Andreas

AU - Beyer, Thomas

PY - 2013/2

Y1 - 2013/2

N2 - Purpose: Integrated whole-body PET/MRI tomographs have become available. PET/MR imaging has the potential to supplement, or even replace combined PET/CT imaging in selected clinical indications. However, this is true only if methodological pitfalls and image artifacts arising from novel MR-based attenuation correction (MR-AC) are fully understood. Results: Here we present PET/MR image artifacts following routine MR-AC, as most frequently observed in clinical operations of an integrated whole-body PET/MRI system. Conclusion: A clinical adoption of integrated PET/MRI should entail the joint image display and interpretation of MR data, MR-based attenuation maps and uncorrected plus attenuation-corrected PET images in order to recognize potential pitfalls from MR-AC and to ensure clinically accurate image interpretation.

AB - Purpose: Integrated whole-body PET/MRI tomographs have become available. PET/MR imaging has the potential to supplement, or even replace combined PET/CT imaging in selected clinical indications. However, this is true only if methodological pitfalls and image artifacts arising from novel MR-based attenuation correction (MR-AC) are fully understood. Results: Here we present PET/MR image artifacts following routine MR-AC, as most frequently observed in clinical operations of an integrated whole-body PET/MRI system. Conclusion: A clinical adoption of integrated PET/MRI should entail the joint image display and interpretation of MR data, MR-based attenuation maps and uncorrected plus attenuation-corrected PET images in order to recognize potential pitfalls from MR-AC and to ensure clinically accurate image interpretation.

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DO - 10.1007/s10334-012-0345-4

M3 - Journal article

C2 - 22996323

SN - 0968-5243

VL - 26

SP - 173

EP - 181

JO - Magnetic Resonance Materials in Physics, Biology, and Medicine

JF - Magnetic Resonance Materials in Physics, Biology, and Medicine

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Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI

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