TY - JOUR
T1 - Illness management and recovery
T2 - Clinical outcomes of a randomized clinical trial in community mental health centers
AU - Dalum, Helle Stentoft
AU - Waldemar, Anna Kristine
AU - Korsbek, Lisa
AU - Hjorthøj, Carsten
AU - Mikkelsen, John Hagel
AU - Thomsen, Karin
AU - Kistrup, Kristen
AU - Olander, Mette
AU - Lindschou, Jane
AU - Nordentoft, Merete
AU - Eplov, Lene Falgaard
PY - 2018/4
Y1 - 2018/4
N2 - OBJECTIVE: Illness Management and Recovery (IMR) is a psychosocial intervention with a recovery-oriented approach. The program has been evaluated in different settings; however evidence for the effects of IMR is still deficient. The aim of this trial was to investigate the benefits and harms of the IMR program compared with treatment as usual in Danish patients with schizophrenia or bipolar disorder.METHOD: The trial was designed as a randomized, assessor-blinded, multi-center, clinical trial investigating the IMR program compared with usual treatment. 198 people diagnosed with schizophrenia or bipolar disorder participated. The primary outcome was the Global Assessment of Functioning (GAF-F) at the end of intervention and the secondary and explorative outcomes included severity of symptoms and service utilization.RESULTS: IMR had no significant effect on functioning, symptoms, substance use or service utilization.CONCLUSION: This randomized trial contributes to the evidence base of IMR by providing a methodological solid base for its conclusions; however the trial has some important limitations. More research is needed to get a firm answer on the effectiveness of the IMR.
AB - OBJECTIVE: Illness Management and Recovery (IMR) is a psychosocial intervention with a recovery-oriented approach. The program has been evaluated in different settings; however evidence for the effects of IMR is still deficient. The aim of this trial was to investigate the benefits and harms of the IMR program compared with treatment as usual in Danish patients with schizophrenia or bipolar disorder.METHOD: The trial was designed as a randomized, assessor-blinded, multi-center, clinical trial investigating the IMR program compared with usual treatment. 198 people diagnosed with schizophrenia or bipolar disorder participated. The primary outcome was the Global Assessment of Functioning (GAF-F) at the end of intervention and the secondary and explorative outcomes included severity of symptoms and service utilization.RESULTS: IMR had no significant effect on functioning, symptoms, substance use or service utilization.CONCLUSION: This randomized trial contributes to the evidence base of IMR by providing a methodological solid base for its conclusions; however the trial has some important limitations. More research is needed to get a firm answer on the effectiveness of the IMR.
KW - Adult
KW - Aged
KW - Community Mental Health Centers/organization & administration
KW - Female
KW - Humans
KW - Male
KW - Mental Disorders/therapy
KW - Middle Aged
KW - Remission Induction/methods
KW - Young Adult
U2 - 10.1371/journal.pone.0194027
DO - 10.1371/journal.pone.0194027
M3 - Journal article
C2 - 29621284
SN - 1932-6203
VL - 13
JO - PLoS Computational Biology
JF - PLoS Computational Biology
IS - 4
M1 - e0194027
ER -