Identification of hazelnut major allergens in sensitive patients with positive double-blind, placebo-controlled food challenge results

Elide A Pastorello, Stefan Vieths, Valerio Pravettoni, Laura Farioli, Chiara Trambaioli, Donatella Fortunato, Dirk Lüttkopf, Marianna Calamari, Raffaella Ansaloni, Joseph Scibilia, Barbara K Ballmer-Weber, Lars K. Poulsen, Brunello Wütrich, Kirsten Skamstrup Hansen, Anna Maria Robino, Claudio Ortolani, Amedeo Conti

    185 Citations (Scopus)

    Abstract

    The hazelnut major allergens identified to date are an 18-kd protein homologous to Bet v 1 and a 14-kd allergen homologous to Bet v 2. No studies have reported hazelnut allergens recognized in patients with positive double-blind, placebo-controlled food challenge (DBPCFC) results or in patients allergic to hazelnut but not to birch.
    Original languageEnglish
    JournalThe Journal of allergy and clinical immunology
    Volume109
    Issue number3
    Pages (from-to)563-70
    Number of pages8
    ISSN0091-6749
    Publication statusPublished - Mar 2002

    Keywords

    • Allergens
    • Amino Acid Sequence
    • Anaphylaxis
    • Cross Reactions
    • Double-Blind Method
    • Electrophoresis, Polyacrylamide Gel
    • Humans
    • Immunoblotting
    • Immunoglobulin E
    • Molecular Sequence Data
    • Nut Hypersensitivity
    • Nuts

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