Identification and Characterization of Glucosinolate Transporters

Morten Egevang Jørgensen

Identification and Characterization of Glucosinolate Transporters

Morten Egevang Jørgensen

Abstract

Plants synthesize thousands of specialized metabolites that are crucial for plant survival. Glucosinolates are specialized defence-metabolites found in plants of the order Brassicales including the model plant Arabidopsis thaliana. Tissue-specific accumulation of glucosinolates is an essential part of plant defence, and the distribution pattern reflects the individual contributions from biosynthesis, transport and turnover. However, little is known about how and to what extent transport processes contribute to establishing these distribution patterns. With the recent identification of AtGTR1 and AtGTR2, two high-affinity glucosinolate transporters, a new molecular tool was provided to study glucosinlate transport in A. thaliana. This thesis contains 6 papers where transporter proteins are identified and characterized biochemically and genetically.

Original language	English

Publisher	Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen
Publication status	Published - 2014

Cite this

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title = "Identification and Characterization of Glucosinolate Transporters",

abstract = "Plants synthesize thousands of specialized metabolites that are crucial for plant survival. Glucosinolates are specialized defence-metabolites found in plants of the order Brassicales including the model plant Arabidopsis thaliana. Tissue-specific accumulation of glucosinolates is an essential part of plant defence, and the distribution pattern reflects the individual contributions from biosynthesis, transport and turnover. However, little is known about how and to what extent transport processes contribute to establishing these distribution patterns. With the recent identification of AtGTR1 and AtGTR2, two high-affinity glucosinolate transporters, a new molecular tool was provided to study glucosinlate transport in A. thaliana. This thesis contains 6 papers where transporter proteins are identified and characterized biochemically and genetically.",

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TY - BOOK

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AU - Jørgensen, Morten Egevang

PY - 2014

Y1 - 2014

N2 - Plants synthesize thousands of specialized metabolites that are crucial for plant survival. Glucosinolates are specialized defence-metabolites found in plants of the order Brassicales including the model plant Arabidopsis thaliana. Tissue-specific accumulation of glucosinolates is an essential part of plant defence, and the distribution pattern reflects the individual contributions from biosynthesis, transport and turnover. However, little is known about how and to what extent transport processes contribute to establishing these distribution patterns. With the recent identification of AtGTR1 and AtGTR2, two high-affinity glucosinolate transporters, a new molecular tool was provided to study glucosinlate transport in A. thaliana. This thesis contains 6 papers where transporter proteins are identified and characterized biochemically and genetically.

AB - Plants synthesize thousands of specialized metabolites that are crucial for plant survival. Glucosinolates are specialized defence-metabolites found in plants of the order Brassicales including the model plant Arabidopsis thaliana. Tissue-specific accumulation of glucosinolates is an essential part of plant defence, and the distribution pattern reflects the individual contributions from biosynthesis, transport and turnover. However, little is known about how and to what extent transport processes contribute to establishing these distribution patterns. With the recent identification of AtGTR1 and AtGTR2, two high-affinity glucosinolate transporters, a new molecular tool was provided to study glucosinlate transport in A. thaliana. This thesis contains 6 papers where transporter proteins are identified and characterized biochemically and genetically.

M3 - Ph.D. thesis

BT - Identification and Characterization of Glucosinolate Transporters

PB - Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen

ER -