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Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation
C L Hawkins,
Michael Jonathan Davies
Inflammation, Metabolism and Oxidation
256
Citations (Scopus)
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Dive into the research topics of 'Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation'. Together they form a unique fingerprint.
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Medicine & Life Sciences
Hypochlorous Acid
100%
Nitrogen
68%
Lysine
67%
Proteins
25%
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
24%
Methionine
18%
Amino Acids, Peptides, and Proteins
16%
Glutathione
15%
Chloramines
15%
chloramine
14%
Spin Trapping
13%
Oxidants
9%
Uric Acid
8%
Hydrogen Peroxide
8%
Bilirubin
8%
Peroxidase
8%
Digestion
7%
Monocytes
7%
Neutrophils
6%
Antioxidants
6%
Amino Acids
6%
Enzymes
4%
Chemical Compounds
Lysine Residue
77%
Hypochlorite
60%
Fragmentation
57%
Protein
28%
Chloramine
28%
Trolox
25%
Ascorbate
22%
Methionine
20%
Glutathione
17%
Homolysis
12%
Spin Trapping
11%
Bilirubin
11%
Lysine
9%
Amino Groups
8%
Hydrogen Peroxide
7%
Antioxidant Agent
7%
Acid
6%
Cleavage
6%
Peptide
5%
Reaction Yield
4%