Hunting for the high-affinity state of G-protein-coupled receptors with agonist tracers: Theoretical and practical considerations for positron emission tomography imaging

Vladimir Shalgunov, Aren van Waarde, Jan Booij, Martin C. Michel, Rudi A. J. O. Dierckx, Philip H. Elsinga

8 Citations (Scopus)
3 Downloads (Pure)
Original languageEnglish
JournalMedicinal Research Reviews
Volume39
Issue number3
Pages (from-to)1014-1052
ISSN0198-6325
DOIs
Publication statusPublished - May 2019
Externally publishedYes

Keywords

  • agonist high-affinity state
  • experimental design
  • G-protein-coupled receptors
  • human brain
  • neurotransmitters
  • positron emission tomography

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