Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice

Ida Søgaard Larsen; Andreas Mæchel Fritzen; Christian Strini Carl; Marianne Agerholm; Mads Thue Fejerskov Damgaard; Jacob Bak Holm; Andre Marette; Peter Nordkild; Bente Kiens; Karsten Kristiansen; Jan Wehkamp; Benjamin Anderschou Holbech Jensen

doi:10.1152/ajpendo.00019.2019

Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice

Ida Søgaard Larsen, Andreas Mæchel Fritzen, Christian Strini Carl, Marianne Agerholm, Mads Thue Fejerskov Damgaard, Jacob Bak Holm, Andre Marette, Peter Nordkild, Bente Kiens, Karsten Kristiansen, Jan Wehkamp, Benjamin Anderschou Holbech Jensen^*

^*Corresponding author for this work

8 Citations (Scopus)

Original language	English
Journal	American Journal of Physiology: Endocrinology and Metabolism
Volume	317
Issue number	1
Pages (from-to)	E42-E52
Number of pages	11
ISSN	0193-1849
DOIs	https://doi.org/10.1152/ajpendo.00019.2019
Publication status	Published - 2019

Keywords

Faculty of Science
Human defensins
Diet induced obesity
Insulin resistance
NAFLD
Host-microbe interactions

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1152/ajpendo.00019.2019

ajpendo.00019.2019Final published version, 0.98 MB

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Larsen, I. S., Fritzen, A. M., Carl, C. S., Agerholm, M., Damgaard, M. T. F., Holm, J. B., Marette, A., Nordkild, P., Kiens, B., Kristiansen, K., Wehkamp, J., & Jensen, B. A. H. (2019). Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice. American Journal of Physiology: Endocrinology and Metabolism, 317(1), E42-E52. https://doi.org/10.1152/ajpendo.00019.2019

Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice. / Larsen, Ida Søgaard; Fritzen, Andreas Mæchel ; Carl, Christian Strini et al.
In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 317, No. 1, 2019, p. E42-E52.

Research output: Contribution to journal › Journal article › Research › peer-review

Larsen, IS, Fritzen, AM , Carl, CS, Agerholm, M, Damgaard, MTF, Holm, JB, Marette, A, Nordkild, P, Kiens, B , Kristiansen, K, Wehkamp, J & Jensen, BAH 2019, 'Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice', American Journal of Physiology: Endocrinology and Metabolism, vol. 317, no. 1, pp. E42-E52. https://doi.org/10.1152/ajpendo.00019.2019

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title = "Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice",

keywords = "Faculty of Science, Human defensins, Diet induced obesity, Insulin resistance, NAFLD, Host-microbe interactions",

author = "Larsen, {Ida S{\o}gaard} and Fritzen, {Andreas M{\ae}chel} and Carl, {Christian Strini} and Marianne Agerholm and Damgaard, {Mads Thue Fejerskov} and Holm, {Jacob Bak} and Andre Marette and Peter Nordkild and Bente Kiens and Karsten Kristiansen and Jan Wehkamp and Jensen, {Benjamin Anderschou Holbech}",

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T1 - Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice

AU - Larsen, Ida Søgaard

AU - Fritzen, Andreas Mæchel

AU - Carl, Christian Strini

AU - Agerholm, Marianne

AU - Damgaard, Mads Thue Fejerskov

AU - Holm, Jacob Bak

AU - Marette, Andre

AU - Nordkild, Peter

AU - Kiens, Bente

AU - Kristiansen, Karsten

AU - Wehkamp, Jan

AU - Jensen, Benjamin Anderschou Holbech

N1 - CURIS 2019 NEXS 221

PY - 2019

Y1 - 2019

KW - Faculty of Science

KW - Human defensins

KW - Diet induced obesity

KW - Insulin resistance

KW - NAFLD

KW - Host-microbe interactions

U2 - 10.1152/ajpendo.00019.2019

DO - 10.1152/ajpendo.00019.2019

M3 - Journal article

C2 - 30860877

SN - 0193-1849

VL - 317

SP - E42-E52

JO - American Journal of Physiology: Endocrinology and Metabolism

JF - American Journal of Physiology: Endocrinology and Metabolism

IS - 1

ER -

Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice

Keywords

UN SDGs

Access to Document

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