Abstract
The field of human ancient DNA (aDNA) has moved from mitochondrial sequencing that suffered from contamination and provided limited biological insights, to become a fully genomic discipline that is changing our conception of human history. Recent successes include the sequencing of extinct hominins, and true population genomic studies of Bronze Age populations. Among the emerging areas of aDNA research, the analysis of past epigenomes is set to provide more new insights into human adaptation and disease susceptibility through time. Starting as a mere curiosity, ancient human genetics has become a major player in the understanding of our evolutionary history.
Original language | English |
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Article number | 20150484 |
Journal | Royal Society of London. Philosophical Transactions B. Biological Sciences |
Volume | 372 |
Issue number | 1713 |
Number of pages | 11 |
ISSN | 0962-8436 |
DOIs | |
Publication status | Published - 5 Feb 2017 |