Home blood pressure in pregnancy - the upper reference limit

Marianne Vestgaard; Julie Carstens Søholm; Sidse Kjærhus Nørgaard; Björg Ásbjörnsdóttir; Lene Ringholm; Peter Damm; Elisabeth R. Mathiesen

doi:10.1097/MBP.0000000000000386

Home blood pressure in pregnancy - the upper reference limit

Marianne Vestgaard, Julie Carstens Søholm, Sidse Kjærhus Nørgaard, Björg Ásbjörnsdóttir, Lene Ringholm, Peter Damm, Elisabeth R. Mathiesen

Department of Clinical Medicine

Abstract

Objectives: To investigate whether the upper home blood pressure reference limit in healthy pregnant women correspond to 135/85 mmHg as used when diagnosing white coat hypertension outside pregnancy. Methods: In this prospective observational study 103 healthy, singleton pregnant women with a mean age of 32 ± 4 (±SD) years and with a median pre-pregnancy body mass index of 21 (interquartile range 20–24) kg/m² were included. Home blood pressure was measured with the device Microlife® BP 3A Plus twice daily for three days (18 measurements in total) in addition to routine office blood pressure measurements in early (median 12⁺¹ (weeks^+days)), mid (20⁺⁰) and late pregnancy (35⁺³). Upper blood pressure reference limits were calculated as mean +2 SD. Results: Office blood pressure versus home blood pressure were 115 ± 11/72 ± 7 versus 103 ± 7/64 ± 5 mmHg in early pregnancy, 112 ± 11/74 ± 7 versus 102 ± 7/63 ± 5 mmHg in mid pregnancy and 118 ± 11/75 ± 8 versus 107 ± 8/66 ± 6 mmHg in late pregnancy. The mean difference between office blood pressure and home blood pressure was 10 mmHg. In late pregnancy, the upper reference limit was 140/91 mmHg for office blood pressure and 123/78 mmHg for home blood pressure with slightly lower values in early and mid pregnancy, respectively. Conclusion: In late pregnancy, the upper home blood pressure reference limit in a population of healthy women was 123/78 mmHg. This value questions the generally proposed level of 135/85 mmHg to define white coat hypertension in pregnancy.

Original language	English
Journal	Blood Pressure Monitoring
Volume	24
Issue number	4
Pages (from-to)	191-198
Number of pages	8
ISSN	1359-5237
DOIs	https://doi.org/10.1097/MBP.0000000000000386
Publication status	Published - 1 Aug 2019

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10.1097/MBP.0000000000000386

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title = "Home blood pressure in pregnancy - the upper reference limit",

abstract = "Objectives: To investigate whether the upper home blood pressure reference limit in healthy pregnant women correspond to 135/85 mmHg as used when diagnosing white coat hypertension outside pregnancy. Methods: In this prospective observational study 103 healthy, singleton pregnant women with a mean age of 32 ± 4 (±SD) years and with a median pre-pregnancy body mass index of 21 (interquartile range 20–24) kg/m2 were included. Home blood pressure was measured with the device Microlife{\textregistered} BP 3A Plus twice daily for three days (18 measurements in total) in addition to routine office blood pressure measurements in early (median 12+1 (weeks+days)), mid (20+0) and late pregnancy (35+3). Upper blood pressure reference limits were calculated as mean +2 SD. Results: Office blood pressure versus home blood pressure were 115 ± 11/72 ± 7 versus 103 ± 7/64 ± 5 mmHg in early pregnancy, 112 ± 11/74 ± 7 versus 102 ± 7/63 ± 5 mmHg in mid pregnancy and 118 ± 11/75 ± 8 versus 107 ± 8/66 ± 6 mmHg in late pregnancy. The mean difference between office blood pressure and home blood pressure was 10 mmHg. In late pregnancy, the upper reference limit was 140/91 mmHg for office blood pressure and 123/78 mmHg for home blood pressure with slightly lower values in early and mid pregnancy, respectively. Conclusion: In late pregnancy, the upper home blood pressure reference limit in a population of healthy women was 123/78 mmHg. This value questions the generally proposed level of 135/85 mmHg to define white coat hypertension in pregnancy.",

author = "Marianne Vestgaard and {Carstens S{\o}holm}, Julie and {Kj{\ae}rhus N{\o}rgaard}, Sidse and Bj{\"o}rg {\'A}sbj{\"o}rnsd{\'o}ttir and Lene Ringholm and Peter Damm and Mathiesen, {Elisabeth R.}",

year = "2019",

month = aug,

day = "1",

doi = "10.1097/MBP.0000000000000386",

language = "English",

volume = "24",

pages = "191--198",

journal = "Blood Pressure Monitoring",

issn = "1359-5237",

publisher = "Lippincott Williams & Wilkins",

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T1 - Home blood pressure in pregnancy - the upper reference limit

AU - Vestgaard, Marianne

AU - Carstens Søholm, Julie

AU - Kjærhus Nørgaard, Sidse

AU - Ásbjörnsdóttir, Björg

AU - Ringholm, Lene

AU - Damm, Peter

AU - Mathiesen, Elisabeth R.

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Objectives: To investigate whether the upper home blood pressure reference limit in healthy pregnant women correspond to 135/85 mmHg as used when diagnosing white coat hypertension outside pregnancy. Methods: In this prospective observational study 103 healthy, singleton pregnant women with a mean age of 32 ± 4 (±SD) years and with a median pre-pregnancy body mass index of 21 (interquartile range 20–24) kg/m2 were included. Home blood pressure was measured with the device Microlife® BP 3A Plus twice daily for three days (18 measurements in total) in addition to routine office blood pressure measurements in early (median 12+1 (weeks+days)), mid (20+0) and late pregnancy (35+3). Upper blood pressure reference limits were calculated as mean +2 SD. Results: Office blood pressure versus home blood pressure were 115 ± 11/72 ± 7 versus 103 ± 7/64 ± 5 mmHg in early pregnancy, 112 ± 11/74 ± 7 versus 102 ± 7/63 ± 5 mmHg in mid pregnancy and 118 ± 11/75 ± 8 versus 107 ± 8/66 ± 6 mmHg in late pregnancy. The mean difference between office blood pressure and home blood pressure was 10 mmHg. In late pregnancy, the upper reference limit was 140/91 mmHg for office blood pressure and 123/78 mmHg for home blood pressure with slightly lower values in early and mid pregnancy, respectively. Conclusion: In late pregnancy, the upper home blood pressure reference limit in a population of healthy women was 123/78 mmHg. This value questions the generally proposed level of 135/85 mmHg to define white coat hypertension in pregnancy.

AB - Objectives: To investigate whether the upper home blood pressure reference limit in healthy pregnant women correspond to 135/85 mmHg as used when diagnosing white coat hypertension outside pregnancy. Methods: In this prospective observational study 103 healthy, singleton pregnant women with a mean age of 32 ± 4 (±SD) years and with a median pre-pregnancy body mass index of 21 (interquartile range 20–24) kg/m2 were included. Home blood pressure was measured with the device Microlife® BP 3A Plus twice daily for three days (18 measurements in total) in addition to routine office blood pressure measurements in early (median 12+1 (weeks+days)), mid (20+0) and late pregnancy (35+3). Upper blood pressure reference limits were calculated as mean +2 SD. Results: Office blood pressure versus home blood pressure were 115 ± 11/72 ± 7 versus 103 ± 7/64 ± 5 mmHg in early pregnancy, 112 ± 11/74 ± 7 versus 102 ± 7/63 ± 5 mmHg in mid pregnancy and 118 ± 11/75 ± 8 versus 107 ± 8/66 ± 6 mmHg in late pregnancy. The mean difference between office blood pressure and home blood pressure was 10 mmHg. In late pregnancy, the upper reference limit was 140/91 mmHg for office blood pressure and 123/78 mmHg for home blood pressure with slightly lower values in early and mid pregnancy, respectively. Conclusion: In late pregnancy, the upper home blood pressure reference limit in a population of healthy women was 123/78 mmHg. This value questions the generally proposed level of 135/85 mmHg to define white coat hypertension in pregnancy.

U2 - 10.1097/MBP.0000000000000386

DO - 10.1097/MBP.0000000000000386

M3 - Journal article

C2 - 31116148

SN - 1359-5237

VL - 24

SP - 191

EP - 198

JO - Blood Pressure Monitoring

JF - Blood Pressure Monitoring

IS - 4

ER -

Home blood pressure in pregnancy - the upper reference limit

Abstract

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