HLA-DP antigens in HIV-infected individuals

Niels Ødum; J Georgsen; L Fugger; J Møller; B K Jakobsen; B Hofmann; P Skinhøj; M Klokker; E Dickmeiss; A Svejgaard

HLA-DP antigens in HIV-infected individuals

Niels Ødum, J Georgsen, L Fugger, J Møller, B K Jakobsen, B Hofmann, P Skinhøj, M Klokker, E Dickmeiss, A Svejgaard

Cell Biology and Physiology

9 Citations (Scopus)

Abstract

We studied the distribution of HLA-DP antigens in 74 HIV-infected Danish homosexual men and 188 ethnically matched healthy individuals, using the primed lymphocyte typing (PLT) technique. Forty of the patients developed AIDS within 3 years after diagnosis, whereas the remaining 34 were healthy or had only minor symptoms for 3 years or more (median observation time was 42 months). HLA-DPwl seemed to be decreased (relative risk = 0.3) in AIDS patients (5.0 per cent) when compared to patients with minor symptoms (14.7 per cent) and healthy controls (14.9 per cent). These differences were, however, not statistically significant. There were no other apparent deviations between patients (or subgroups of patients) and controls.

Original language	English
Journal	Disease Markers
Volume	8
Issue number	3
Pages (from-to)	113-6
Number of pages	3
ISSN	0278-0240
Publication status	Published - 1991

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

@article{695ecde0fd9811ddb219000ea68e967b,

title = "HLA-DP antigens in HIV-infected individuals",

abstract = "We studied the distribution of HLA-DP antigens in 74 HIV-infected Danish homosexual men and 188 ethnically matched healthy individuals, using the primed lymphocyte typing (PLT) technique. Forty of the patients developed AIDS within 3 years after diagnosis, whereas the remaining 34 were healthy or had only minor symptoms for 3 years or more (median observation time was 42 months). HLA-DPwl seemed to be decreased (relative risk = 0.3) in AIDS patients (5.0 per cent) when compared to patients with minor symptoms (14.7 per cent) and healthy controls (14.9 per cent). These differences were, however, not statistically significant. There were no other apparent deviations between patients (or subgroups of patients) and controls.",

author = "Niels {\O}dum and J Georgsen and L Fugger and J M{\o}ller and Jakobsen, {B K} and B Hofmann and P Skinh{\o}j and M Klokker and E Dickmeiss and A Svejgaard",

note = "Keywords: Acquired Immunodeficiency Syndrome; Disease Susceptibility; Genetic Markers; HIV Infections; HLA-DP Antigens; Humans; Lymphocyte Culture Test, Mixed; Male; Risk Factors",

year = "1991",

language = "English",

volume = "8",

pages = "113--6",

journal = "Disease Markers",

issn = "0278-0240",

publisher = "Hindawi Publishing Corporation",

number = "3",

}

TY - JOUR

T1 - HLA-DP antigens in HIV-infected individuals

AU - Ødum, Niels

AU - Georgsen, J

AU - Fugger, L

AU - Møller, J

AU - Jakobsen, B K

AU - Hofmann, B

AU - Skinhøj, P

AU - Klokker, M

AU - Dickmeiss, E

AU - Svejgaard, A

N1 - Keywords: Acquired Immunodeficiency Syndrome; Disease Susceptibility; Genetic Markers; HIV Infections; HLA-DP Antigens; Humans; Lymphocyte Culture Test, Mixed; Male; Risk Factors

PY - 1991

Y1 - 1991

N2 - We studied the distribution of HLA-DP antigens in 74 HIV-infected Danish homosexual men and 188 ethnically matched healthy individuals, using the primed lymphocyte typing (PLT) technique. Forty of the patients developed AIDS within 3 years after diagnosis, whereas the remaining 34 were healthy or had only minor symptoms for 3 years or more (median observation time was 42 months). HLA-DPwl seemed to be decreased (relative risk = 0.3) in AIDS patients (5.0 per cent) when compared to patients with minor symptoms (14.7 per cent) and healthy controls (14.9 per cent). These differences were, however, not statistically significant. There were no other apparent deviations between patients (or subgroups of patients) and controls.

AB - We studied the distribution of HLA-DP antigens in 74 HIV-infected Danish homosexual men and 188 ethnically matched healthy individuals, using the primed lymphocyte typing (PLT) technique. Forty of the patients developed AIDS within 3 years after diagnosis, whereas the remaining 34 were healthy or had only minor symptoms for 3 years or more (median observation time was 42 months). HLA-DPwl seemed to be decreased (relative risk = 0.3) in AIDS patients (5.0 per cent) when compared to patients with minor symptoms (14.7 per cent) and healthy controls (14.9 per cent). These differences were, however, not statistically significant. There were no other apparent deviations between patients (or subgroups of patients) and controls.

M3 - Journal article

C2 - 2148714

SN - 0278-0240

VL - 8

SP - 113

EP - 116

JO - Disease Markers

JF - Disease Markers

IS - 3

ER -

HLA-DP antigens in HIV-infected individuals

Abstract

UN SDGs

Fingerprint

Cite this