Historical epidemiology of hepatitis C virus (HCV) in selected countries

P Bruggmann; T Berg; A L H Øvrehus; C Moreno; C E Brandão Mello; F Roudot-Thoraval; R T Marinho; M Sherman; S D Ryder; J Sperl; U Akarca; I Balık; F Bihl; M Bilodeau; A J Blasco; M Buti; F Calinas; J L Calleja; H Cheinquer; P B Christensen; M Clausen; H S M Coelho; M Cornberg; M E Cramp; G J Dore; W Doss; A S Duberg; M H El-Sayed; G Ergör; G Esmat; C Estes; K Falconer; J Félix; M L G Ferraz; P R Ferreira; S Frankova; J García-Samaniego; J Gerstoft; J A Giria; F L Gonçales; E Gower; M Gschwantler; M Guimarães Pessôa; C Hézode; H Hofer; P Husa; R Idilman; M Kåberg; K D E Kaita; A Kautz; S Kaymakoglu; M Krajden; H Krarup; W Laleman; D Lavanchy; P Lázaro; P Marotta; S Mauss; M C Mendes Correa; B Müllhaupt; R P Myers; F Negro; V Nemecek; N Örmeci; J Parkes; K M Peltekian; A Ramji; H Razavi; N Reis; S K Roberts; W M Rosenberg; R Sarmento-Castro; C Sarrazin; D Semela; G E Shiha; W Sievert; P Stärkel; R E Stauber; A J Thompson; P Urbanek; I van Thiel; H Van Vlierberghe; D Vandijck; W Vogel; I Waked; H Wedemeyer; N Weis; J Wiegand; A Yosry; A Zekry; P Van Damme; S Aleman; S J Hindman

doi:10.1111/jvh.12247

Historical epidemiology of hepatitis C virus (HCV) in selected countries

P Bruggmann, T Berg, A L H Øvrehus, C Moreno, C E Brandão Mello, F Roudot-Thoraval, R T Marinho, M Sherman, S D Ryder, J Sperl, U Akarca, I Balık, F Bihl, M Bilodeau, A J Blasco, M Buti, F Calinas, J L Calleja, H Cheinquer, P B ChristensenM Clausen, H S M Coelho, M Cornberg, M E Cramp, G J Dore, W Doss, A S Duberg, M H El-Sayed, G Ergör, G Esmat, C Estes, K Falconer, J Félix, M L G Ferraz, P R Ferreira, S Frankova, J García-Samaniego, J Gerstoft, J A Giria, F L Gonçales, E Gower, M Gschwantler, M Guimarães Pessôa, C Hézode, H Hofer, P Husa, R Idilman, M Kåberg, K D E Kaita, A Kautz, S Kaymakoglu, M Krajden, H Krarup, W Laleman, D Lavanchy, P Lázaro, P Marotta, S Mauss, M C Mendes Correa, B Müllhaupt, R P Myers, F Negro, V Nemecek, N Örmeci, J Parkes, K M Peltekian, A Ramji, H Razavi, N Reis, S K Roberts, W M Rosenberg, R Sarmento-Castro, C Sarrazin, D Semela, G E Shiha, W Sievert, P Stärkel, R E Stauber, A J Thompson, P Urbanek, I van Thiel, H Van Vlierberghe, D Vandijck, W Vogel, I Waked, H Wedemeyer, N Weis, J Wiegand, A Yosry, A Zekry, P Van Damme, S Aleman, S J Hindman

Department of Clinical Medicine

200 Citations (Scopus)

Abstract

Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.

Original language	English
Journal	Journal of Viral Hepatitis
Volume	21 S
Issue number	s1
Pages (from-to)	5-33
Number of pages	29
ISSN	1352-0504
DOIs	https://doi.org/10.1111/jvh.12247
Publication status	Published - 1 May 2014

Keywords

Antiviral Agents
Global Health
Hepatitis C, Chronic
Humans
Incidence
Liver Transplantation
Prevalence
Survival Analysis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/jvh.12247

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Bruggmann, P., Berg, T., Øvrehus, A. L. H., Moreno, C., Brandão Mello, C. E., Roudot-Thoraval, F., Marinho, R. T., Sherman, M., Ryder, S. D., Sperl, J., Akarca, U., Balık, I., Bihl, F., Bilodeau, M., Blasco, A. J., Buti, M., Calinas, F., Calleja, J. L., Cheinquer, H., ... Hindman, S. J. (2014). Historical epidemiology of hepatitis C virus (HCV) in selected countries. Journal of Viral Hepatitis, 21 S(s1), 5-33. https://doi.org/10.1111/jvh.12247

Bruggmann, P, Berg, T, Øvrehus, ALH, Moreno, C, Brandão Mello, CE, Roudot-Thoraval, F, Marinho, RT, Sherman, M, Ryder, SD, Sperl, J, Akarca, U, Balık, I, Bihl, F, Bilodeau, M, Blasco, AJ, Buti, M, Calinas, F, Calleja, JL, Cheinquer, H, Christensen, PB, Clausen, M, Coelho, HSM, Cornberg, M, Cramp, ME, Dore, GJ, Doss, W, Duberg, AS, El-Sayed, MH, Ergör, G, Esmat, G, Estes, C, Falconer, K, Félix, J, Ferraz, MLG, Ferreira, PR, Frankova, S, García-Samaniego, J, Gerstoft, J, Giria, JA, Gonçales, FL, Gower, E, Gschwantler, M, Guimarães Pessôa, M, Hézode, C, Hofer, H, Husa, P, Idilman, R, Kåberg, M, Kaita, KDE, Kautz, A, Kaymakoglu, S, Krajden, M, Krarup, H, Laleman, W, Lavanchy, D, Lázaro, P, Marotta, P, Mauss, S, Mendes Correa, MC, Müllhaupt, B, Myers, RP, Negro, F, Nemecek, V, Örmeci, N, Parkes, J, Peltekian, KM, Ramji, A, Razavi, H, Reis, N, Roberts, SK, Rosenberg, WM, Sarmento-Castro, R, Sarrazin, C, Semela, D, Shiha, GE, Sievert, W, Stärkel, P, Stauber, RE, Thompson, AJ, Urbanek, P, van Thiel, I, Van Vlierberghe, H, Vandijck, D, Vogel, W, Waked, I, Wedemeyer, H, Weis, N, Wiegand, J, Yosry, A, Zekry, A, Van Damme, P, Aleman, S & Hindman, SJ 2014, 'Historical epidemiology of hepatitis C virus (HCV) in selected countries', Journal of Viral Hepatitis, vol. 21 S, no. s1, pp. 5-33. https://doi.org/10.1111/jvh.12247

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abstract = "Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.",

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language = "English",

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T1 - Historical epidemiology of hepatitis C virus (HCV) in selected countries

AU - Bruggmann, P

AU - Berg, T

AU - Øvrehus, A L H

AU - Moreno, C

AU - Brandão Mello, C E

AU - Roudot-Thoraval, F

AU - Marinho, R T

AU - Sherman, M

AU - Ryder, S D

AU - Sperl, J

AU - Akarca, U

AU - Balık, I

AU - Bihl, F

AU - Bilodeau, M

AU - Blasco, A J

AU - Buti, M

AU - Calinas, F

AU - Calleja, J L

AU - Cheinquer, H

AU - Christensen, P B

AU - Clausen, M

AU - Coelho, H S M

AU - Cornberg, M

AU - Cramp, M E

AU - Dore, G J

AU - Doss, W

AU - Duberg, A S

AU - El-Sayed, M H

AU - Ergör, G

AU - Esmat, G

AU - Estes, C

AU - Falconer, K

AU - Félix, J

AU - Ferraz, M L G

AU - Ferreira, P R

AU - Frankova, S

AU - García-Samaniego, J

AU - Gerstoft, J

AU - Giria, J A

AU - Gonçales, F L

AU - Gower, E

AU - Gschwantler, M

AU - Guimarães Pessôa, M

AU - Hézode, C

AU - Hofer, H

AU - Husa, P

AU - Idilman, R

AU - Kåberg, M

AU - Kaita, K D E

AU - Kautz, A

AU - Kaymakoglu, S

AU - Krajden, M

AU - Krarup, H

AU - Laleman, W

AU - Lavanchy, D

AU - Lázaro, P

AU - Marotta, P

AU - Mauss, S

AU - Mendes Correa, M C

AU - Müllhaupt, B

AU - Myers, R P

AU - Negro, F

AU - Nemecek, V

AU - Örmeci, N

AU - Parkes, J

AU - Peltekian, K M

AU - Ramji, A

AU - Razavi, H

AU - Reis, N

AU - Roberts, S K

AU - Rosenberg, W M

AU - Sarmento-Castro, R

AU - Sarrazin, C

AU - Semela, D

AU - Shiha, G E

AU - Sievert, W

AU - Stärkel, P

AU - Stauber, R E

AU - Thompson, A J

AU - Urbanek, P

AU - van Thiel, I

AU - Van Vlierberghe, H

AU - Vandijck, D

AU - Vogel, W

AU - Waked, I

AU - Wedemeyer, H

AU - Weis, N

AU - Wiegand, J

AU - Yosry, A

AU - Zekry, A

AU - Van Damme, P

AU - Aleman, S

AU - Hindman, S J

PY - 2014/5/1

Y1 - 2014/5/1

N2 - Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.

AB - Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.

KW - Antiviral Agents

KW - Global Health

KW - Hepatitis C, Chronic

KW - Humans

KW - Incidence

KW - Liver Transplantation

KW - Prevalence

KW - Survival Analysis

U2 - 10.1111/jvh.12247

DO - 10.1111/jvh.12247

M3 - Journal article

C2 - 24713004

SN - 1352-0504

VL - 21 S

SP - 5

EP - 33

JO - Journal of Viral Hepatitis

JF - Journal of Viral Hepatitis

IS - s1

ER -

Historical epidemiology of hepatitis C virus (HCV) in selected countries

Abstract

Keywords

UN SDGs

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