Histone modifications: Cycling with chromosomal replication

1 Citation (Scopus)

Abstract

Histone modifications tend to be lost during chromosome duplication. Several recent studies suggest that the RNA interference pathway becomes active during the weakened transcriptional repression occurring at centromeres in S phase, resulting in the re-establishment of histone modifications that direct the formation of heterochromatin.
Original languageEnglish
JournalCurrent Biology
Volume18
Issue number9
Pages (from-to)380-382
Number of pages3
ISSN0960-9822
DOIs
Publication statusPublished - 2008

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