Abstract
Histone modifications tend to be lost during chromosome duplication. Several recent studies suggest that the RNA interference pathway becomes active during the weakened transcriptional repression occurring at centromeres in S phase, resulting in the re-establishment of histone modifications that direct the formation of heterochromatin.
Original language | English |
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Journal | Current Biology |
Volume | 18 |
Issue number | 9 |
Pages (from-to) | 380-382 |
Number of pages | 3 |
ISSN | 0960-9822 |
DOIs | |
Publication status | Published - 2008 |