Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise

Carsten Roepstorff; Maja Thiele; Thore Hillig; Henriette Pilegaard; Erik Richter; Jørgen Wojtaszewski; Bente Kiens

doi:10.1113/jphysiol.2006.108720

Higher skeletal muscle alpha₂AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise

Carsten Roepstorff, Maja Thiele, Thore Hillig, Henriette Pilegaard, Erik Richter, Jørgen Wojtaszewski, Bente Kiens

114 Citations (Scopus)

Abstract

5'AMP-activated protein kinase (AMPK) is an energy sensor activatedby perturbed cellular energy status such as during muscle contraction.Activated AMPK is thought to regulate several key metabolicpathways. We used sex comparison to investigate whether AMPKsignalling in skeletal muscle regulates fat oxidation duringexercise.

Original language	English
Journal	Journal of Physiology
Volume	574
Issue number	1
Pages (from-to)	125-138
Number of pages	14
ISSN	0022-3751
DOIs	https://doi.org/10.1113/jphysiol.2006.108720
Publication status	Published - 2006

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10.1113/jphysiol.2006.108720

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title = "Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise",

abstract = "5'AMP-activated protein kinase (AMPK) is an energy sensor activated by perturbed cellular energy status such as during muscle contraction. Activated AMPK is thought to regulate several key metabolic pathways. We used sex comparison to investigate whether AMPK signalling in skeletal muscle regulates fat oxidation during exercise.",

author = "Carsten Roepstorff and Maja Thiele and Thore Hillig and Henriette Pilegaard and Erik Richter and J{\o}rgen Wojtaszewski and Bente Kiens",

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AU - Roepstorff, Carsten

AU - Thiele, Maja

AU - Hillig, Thore

AU - Pilegaard, Henriette

AU - Richter, Erik

AU - Wojtaszewski, Jørgen

AU - Kiens, Bente

N1 - PUF 2006 5200 018

PY - 2006

Y1 - 2006

N2 - 5'AMP-activated protein kinase (AMPK) is an energy sensor activated by perturbed cellular energy status such as during muscle contraction. Activated AMPK is thought to regulate several key metabolic pathways. We used sex comparison to investigate whether AMPK signalling in skeletal muscle regulates fat oxidation during exercise.

AB - 5'AMP-activated protein kinase (AMPK) is an energy sensor activated by perturbed cellular energy status such as during muscle contraction. Activated AMPK is thought to regulate several key metabolic pathways. We used sex comparison to investigate whether AMPK signalling in skeletal muscle regulates fat oxidation during exercise.

U2 - 10.1113/jphysiol.2006.108720

DO - 10.1113/jphysiol.2006.108720

M3 - Journal article

SN - 0022-3751

VL - 574

SP - 125

EP - 138

JO - The Journal of Physiology

JF - The Journal of Physiology

IS - 1

ER -

Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise

Abstract

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Higher skeletal muscle alpha₂AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise