High prevalence of Ancylostoma ceylanicum hookworm infections in humans, Cambodia, 2012

TY - JOUR

T1 - High prevalence of Ancylostoma ceylanicum hookworm infections in humans, Cambodia, 2012

AU - Inpankaew, Tawin

AU - Schär, Fabian

AU - Dalsgaard, Anders

AU - Khieu, Virak

AU - Chimnoi, Wissanuwat

AU - Chhoun, Chamnan

AU - Sok, Daream

AU - Marti, Hanspeter

AU - Muth, Sinuon

AU - Odermatt, Peter

AU - Traub, Rebecca J.

PY - 2014/6

Y1 - 2014/6

N2 - Ancylostoma ceylanicum, a hookworm of canids and felids in Asia, is becoming the second most common hookworm infecting humans. In 2012, we investigated the prevalence and infection dynamics of and risk factors for hookworm infections in humans and dogs in a rural Cambodian village. Over 57% of the population was infected with hookworms; of those, 52% harbored A. ceylanicum hookworms. The greatest intensities of A. ceylanicum eggs were in persons 21-30 years of age. Over 90% of dogs also harbored A. ceylanicum hookworms. Characterization of the cytochrome oxidase-1 gene divided isolates of A. ceylanicum hookworms into 2 groups, 1 containing isolates from humans only and the other a mix of isolates from humans and animals. We hypothesize that preventative chemotherapy in the absence of concurrent hygiene and animal health programs may be a factor leading to emergence of A. ceylanicum infections; thus, we advocate for a One Health approach to control this zoonosis.

AB - Ancylostoma ceylanicum, a hookworm of canids and felids in Asia, is becoming the second most common hookworm infecting humans. In 2012, we investigated the prevalence and infection dynamics of and risk factors for hookworm infections in humans and dogs in a rural Cambodian village. Over 57% of the population was infected with hookworms; of those, 52% harbored A. ceylanicum hookworms. The greatest intensities of A. ceylanicum eggs were in persons 21-30 years of age. Over 90% of dogs also harbored A. ceylanicum hookworms. Characterization of the cytochrome oxidase-1 gene divided isolates of A. ceylanicum hookworms into 2 groups, 1 containing isolates from humans only and the other a mix of isolates from humans and animals. We hypothesize that preventative chemotherapy in the absence of concurrent hygiene and animal health programs may be a factor leading to emergence of A. ceylanicum infections; thus, we advocate for a One Health approach to control this zoonosis.

KW - Faculty of Health and Medical Sciences

KW - Cambodia

KW - Dogs

KW - Gastrointestinal parasites

KW - Pigs

KW - Zoonosis

U2 - 10.3201/eid2006.131770

DO - 10.3201/eid2006.131770

M3 - Journal article

C2 - 24865815

SN - 1080-6040

VL - 20

SP - 976

EP - 982

JO - Emerging Infectious Diseases (Online)

JF - Emerging Infectious Diseases (Online)

IS - 6

ER -