High-affinity human leucocyte antigen class I binding variola-derived peptides induce CD4+ T cell responses more than 30 years post-vaccinia virus vaccination

M Wang, S T Tang, O Lund, M H Dziegiel, S Buus, M H Claesson

15 Citations (Scopus)

Abstract

Interferon-gamma secreting T lymphocytes against pox virus-derived synthetic 9-mer peptides were tested by enzyme-linked immunospot in peripheral blood of individuals vaccinated with vaccinia virus more than 30 years ago. The peptides were characterized biochemically as high-affinity human leucocyte antigen (HLA) class I binders (K(D)
Original languageEnglish
JournalClinical and Experimental Immunology
Volume155
Issue number3
Pages (from-to)441-6
Number of pages6
ISSN0009-9104
DOIs
Publication statusPublished - 2009

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