Haptocorrin in humans

Anne L Morkbak; Steen Seier Poulsen; Ebba Nexo

doi:10.1515/CCLM.2007.343

Haptocorrin in humans

Anne L Morkbak, Steen Seier Poulsen, Ebba Nexo

Endocrinology and Metabolism

56 Citations (Scopus)

Abstract

Evolutionary haptocorrin is the youngest of the cobalamin-binding proteins. It evolved by duplication of the intrinsic factor gene and has been identified in most mammals examined. Its ability to bind both cobalamin and analogues is well established, but apart from that, our knowledge concerning its function and its distribution in adult and foetal life is limited. In this study, we present data on the tissue expression of haptocorrin and on the relation between analogues on haptocorrin and vitamin B(12) status in humans.

Original language	English
Journal	Clinical Chemistry and Laboratory Medicine
Volume	45
Issue number	12
Pages (from-to)	1751-9
Number of pages	9
ISSN	1434-6621
DOIs	https://doi.org/10.1515/CCLM.2007.343
Publication status	Published - 1 Jan 2007

Keywords

Enzyme-Linked Immunosorbent Assay
Humans
Immunohistochemistry
Oligonucleotide Array Sequence Analysis
Transcobalamins
Vitamin B 12

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abstract = "Evolutionary haptocorrin is the youngest of the cobalamin-binding proteins. It evolved by duplication of the intrinsic factor gene and has been identified in most mammals examined. Its ability to bind both cobalamin and analogues is well established, but apart from that, our knowledge concerning its function and its distribution in adult and foetal life is limited. In this study, we present data on the tissue expression of haptocorrin and on the relation between analogues on haptocorrin and vitamin B(12) status in humans.",

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AU - Poulsen, Steen Seier

AU - Nexo, Ebba

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N2 - Evolutionary haptocorrin is the youngest of the cobalamin-binding proteins. It evolved by duplication of the intrinsic factor gene and has been identified in most mammals examined. Its ability to bind both cobalamin and analogues is well established, but apart from that, our knowledge concerning its function and its distribution in adult and foetal life is limited. In this study, we present data on the tissue expression of haptocorrin and on the relation between analogues on haptocorrin and vitamin B(12) status in humans.

AB - Evolutionary haptocorrin is the youngest of the cobalamin-binding proteins. It evolved by duplication of the intrinsic factor gene and has been identified in most mammals examined. Its ability to bind both cobalamin and analogues is well established, but apart from that, our knowledge concerning its function and its distribution in adult and foetal life is limited. In this study, we present data on the tissue expression of haptocorrin and on the relation between analogues on haptocorrin and vitamin B(12) status in humans.

KW - Enzyme-Linked Immunosorbent Assay

KW - Humans

KW - Immunohistochemistry

KW - Oligonucleotide Array Sequence Analysis

KW - Transcobalamins

KW - Vitamin B 12

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DO - 10.1515/CCLM.2007.343

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SP - 1751

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JO - Clinical Chemistry and Laboratory Medicine

JF - Clinical Chemistry and Laboratory Medicine

IS - 12

ER -

Haptocorrin in humans

Abstract

Keywords

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