Guidelines on Cerebrospinal Fluid Analysis

Harald Hegen, Charlotte E. Teunissen, Finn Sellebjerg, Hayrettin Tumani, Florian Deisenhammer

1 Citation (Scopus)

Abstract

The examination of cerebrospinal fluid (CSF) is invaluable for the diagnosis of various neurological diseases. Whereas routine parameters such as white blood cell count, CSF/serum albumin quotient, CSF/serum glucose ratio, intrathecal fraction of immunoglobulins or cytological examination are used to obtain an integrative CSF report, there are also single disease-specific CSF biomarkers contributing to clinical diagnosis making. Furthermore, infectious agents can be detected in CSF either directly by microscopy and culture or indirectly by detection of antigens via polymerase chain reaction or of specific antibodies via serology. In this chapter, we discuss the diagnostic value of CSF referring to existing guidelines.

Original languageEnglish
Title of host publicationCerebrospinal Fluid in Clinical Neurology
EditorsFlorian Deisenhammer, Finn Sellebjerg, Charlotte E Teunissen, Hayrettin Tumani
Number of pages22
PublisherSpringer Science+Business Media
Publication date1 Jan 2015
Pages407-428
Chapter24
ISBN (Print)978-3-319-01224-7
ISBN (Electronic)978-3-319-01225-4
DOIs
Publication statusPublished - 1 Jan 2015

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