Guidelines for diagnosis, prevention and treatment of hand eczema

TY - JOUR

T1 - Guidelines for diagnosis, prevention and treatment of hand eczema

AU - Diepgen, Thomas L

AU - Andersen, Klaus E

AU - Chosidow, Oliver

AU - Coenraads, Peter Jan

AU - Elsner, Peter

AU - English, John

AU - Fartasch, Manigé

AU - Gimenez-Arnau, Ana

AU - Nixon, Rosemary

AU - Sasseville, Denis

AU - Agner, Tove

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The guidelines aim to provide advice on the management of hand eczema (HE), using an evidence- and consensus-based approach. The guidelines consider a systematic Cochrane review on interventions for HE, which is based on a systematic search of the published literature (including hand-searching). In addition to the evidence- and consensus-based recommendation on the treatment of HE, the guidelines cover mainly consensus-based diagnostic aspects and preventive measures (primary and secondary prevention). Treatment recommendations include non-pharmacological interventions, topical, physical and systemic treatments. Topical corticosteroids are recommended as first line treatment in the management of HE, however continuous long-term treatment beyond six weeks only when necessary and under careful me-dical supervision. Alitretinoin is recommended as a second line treatment (relative to topical corticosteroids) for patients with severe chronic HE. Randomized control trials (RCT) are missing for other used systemic treatments and comparison of systemic drugs in “head-to-head” RCTs are needed.The guidelines development group is a working group of the European Society of Contact Dermatitis (ESCD) and has carefully tried to reconcile opposite views, define current optimal practice and provide specific recommendations, and meetings have been chaired by a professional moderator of the AWMF (Arbeitsgemeinschaft der Wis-senschaftlichen Medizinischen Fachgesellschaften; Association of the Scientific Medi-cal Societies in Germany).No financial support was given by any medical company. The guidelines are expected to be valid until December 2017 at the latest.

AB - The guidelines aim to provide advice on the management of hand eczema (HE), using an evidence- and consensus-based approach. The guidelines consider a systematic Cochrane review on interventions for HE, which is based on a systematic search of the published literature (including hand-searching). In addition to the evidence- and consensus-based recommendation on the treatment of HE, the guidelines cover mainly consensus-based diagnostic aspects and preventive measures (primary and secondary prevention). Treatment recommendations include non-pharmacological interventions, topical, physical and systemic treatments. Topical corticosteroids are recommended as first line treatment in the management of HE, however continuous long-term treatment beyond six weeks only when necessary and under careful me-dical supervision. Alitretinoin is recommended as a second line treatment (relative to topical corticosteroids) for patients with severe chronic HE. Randomized control trials (RCT) are missing for other used systemic treatments and comparison of systemic drugs in “head-to-head” RCTs are needed.The guidelines development group is a working group of the European Society of Contact Dermatitis (ESCD) and has carefully tried to reconcile opposite views, define current optimal practice and provide specific recommendations, and meetings have been chaired by a professional moderator of the AWMF (Arbeitsgemeinschaft der Wis-senschaftlichen Medizinischen Fachgesellschaften; Association of the Scientific Medi-cal Societies in Germany).No financial support was given by any medical company. The guidelines are expected to be valid until December 2017 at the latest.

KW - Administration, Topical

KW - Adrenal Cortex Hormones

KW - Dermatologic Agents

KW - Dermatology

KW - Eczema

KW - Europe

KW - Evidence-Based Medicine

KW - Germany

KW - Hand Dermatoses

KW - Humans

KW - Practice Guidelines as Topic

KW - Treatment Outcome

U2 - 10.1111/ddg.12510_1

DO - 10.1111/ddg.12510_1

M3 - Journal article

C2 - 25763418

SN - 1610-0379

VL - 13

SP - e1-22

JO - J D D G

JF - J D D G

IS - 1

ER -