Guideline for PET/CT imaging of neuroendocrine neoplasms withGa-DOTA-conjugated somatostatin receptor targeting peptides andF-DOPA

Murat Fani Bozkurt; Irene Virgolini; Sona Balogova; Mohsen Beheshti; Domenico Rubello; Clemens Decristoforo; Valentina Ambrosini; Andreas Kjaer; Roberto Delgado-Bolton; Jolanta Kunikowska; Wim J G Oyen; Arturo Chiti; Francesco Giammarile; Stefano Fanti

doi:10.1007/s00259-017-3728-y

Guideline for PET/CT imaging of neuroendocrine neoplasms withGa-DOTA-conjugated somatostatin receptor targeting peptides andF-DOPA

Murat Fani Bozkurt, Irene Virgolini, Sona Balogova, Mohsen Beheshti, Domenico Rubello, Clemens Decristoforo, Valentina Ambrosini, Andreas Kjaer, Roberto Delgado-Bolton, Jolanta Kunikowska, Wim J G Oyen, Arturo Chiti, Francesco Giammarile, Stefano Fanti

110 Citations (Scopus)

Abstract

PURPOSE & METHODS: Neuroendocrine neoplasms are a heterogenous group of tumours, for which nuclear medicine plays an important role in the diagnostic work-up as well as in the targeted therapeutic options. This guideline is aimed to assist nuclear medicine physicians in recommending, performing, reporting and interpreting the results of somatostatin receptor (SSTR) PET/CT imaging using68Ga-DOTA-conjugated peptides, as well as18F-DOPA imaging for various neuroendocrine neoplasms.

RESULTS & CONCLUSION: The previous procedural guideline by EANM regarding the use PET/CT tumour imaging with68Ga-conjugated peptides has been revised and updated with the relevant and recent literature in the field with contribution of distinguished experts.

Original language	English
Journal	European Journal of Nuclear Medicine and Molecular Imaging
Volume	44
Issue number	9
Pages (from-to)	1588-1601
Number of pages	14
ISSN	1619-7070
DOIs	https://doi.org/10.1007/s00259-017-3728-y
Publication status	Published - 1 Aug 2017

Keywords

Dihydroxyphenylalanine/analogs & derivatives
Gallium Radioisotopes
Heterocyclic Compounds, 1-Ring/chemistry
Humans
Image Interpretation, Computer-Assisted
Neuroendocrine Tumors/diagnostic imaging
Peptides/chemistry
Positron Emission Tomography Computed Tomography/methods
Practice Guidelines as Topic
Quality Control
Receptors, Somatostatin/metabolism
Tissue Distribution

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10.1007/s00259-017-3728-y

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Bozkurt, M. F., Virgolini, I., Balogova, S., Beheshti, M., Rubello, D., Decristoforo, C., Ambrosini, V., Kjaer, A., Delgado-Bolton, R., Kunikowska, J., Oyen, W. J. G., Chiti, A., Giammarile, F., & Fanti, S. (2017). Guideline for PET/CT imaging of neuroendocrine neoplasms withGa-DOTA-conjugated somatostatin receptor targeting peptides andF-DOPA. European Journal of Nuclear Medicine and Molecular Imaging, 44(9), 1588-1601. https://doi.org/10.1007/s00259-017-3728-y

Guideline for PET/CT imaging of neuroendocrine neoplasms withGa-DOTA-conjugated somatostatin receptor targeting peptides andF-DOPA. / Bozkurt, Murat Fani; Virgolini, Irene; Balogova, Sona et al.

In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 44, No. 9, 01.08.2017, p. 1588-1601.

Research output: Contribution to journal › Journal article › Research › peer-review

Bozkurt, MF, Virgolini, I, Balogova, S, Beheshti, M, Rubello, D, Decristoforo, C, Ambrosini, V, Kjaer, A, Delgado-Bolton, R, Kunikowska, J, Oyen, WJG, Chiti, A, Giammarile, F & Fanti, S 2017, 'Guideline for PET/CT imaging of neuroendocrine neoplasms withGa-DOTA-conjugated somatostatin receptor targeting peptides andF-DOPA', European Journal of Nuclear Medicine and Molecular Imaging, vol. 44, no. 9, pp. 1588-1601. https://doi.org/10.1007/s00259-017-3728-y

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abstract = "PURPOSE & METHODS: Neuroendocrine neoplasms are a heterogenous group of tumours, for which nuclear medicine plays an important role in the diagnostic work-up as well as in the targeted therapeutic options. This guideline is aimed to assist nuclear medicine physicians in recommending, performing, reporting and interpreting the results of somatostatin receptor (SSTR) PET/CT imaging using68Ga-DOTA-conjugated peptides, as well as18F-DOPA imaging for various neuroendocrine neoplasms.RESULTS & CONCLUSION: The previous procedural guideline by EANM regarding the use PET/CT tumour imaging with68Ga-conjugated peptides has been revised and updated with the relevant and recent literature in the field with contribution of distinguished experts.",

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T1 - Guideline for PET/CT imaging of neuroendocrine neoplasms withGa-DOTA-conjugated somatostatin receptor targeting peptides andF-DOPA

AU - Bozkurt, Murat Fani

AU - Virgolini, Irene

AU - Balogova, Sona

AU - Beheshti, Mohsen

AU - Rubello, Domenico

AU - Decristoforo, Clemens

AU - Ambrosini, Valentina

AU - Kjaer, Andreas

AU - Delgado-Bolton, Roberto

AU - Kunikowska, Jolanta

AU - Oyen, Wim J G

AU - Chiti, Arturo

AU - Giammarile, Francesco

AU - Fanti, Stefano

PY - 2017/8/1

Y1 - 2017/8/1

N2 - PURPOSE & METHODS: Neuroendocrine neoplasms are a heterogenous group of tumours, for which nuclear medicine plays an important role in the diagnostic work-up as well as in the targeted therapeutic options. This guideline is aimed to assist nuclear medicine physicians in recommending, performing, reporting and interpreting the results of somatostatin receptor (SSTR) PET/CT imaging using68Ga-DOTA-conjugated peptides, as well as18F-DOPA imaging for various neuroendocrine neoplasms.RESULTS & CONCLUSION: The previous procedural guideline by EANM regarding the use PET/CT tumour imaging with68Ga-conjugated peptides has been revised and updated with the relevant and recent literature in the field with contribution of distinguished experts.

AB - PURPOSE & METHODS: Neuroendocrine neoplasms are a heterogenous group of tumours, for which nuclear medicine plays an important role in the diagnostic work-up as well as in the targeted therapeutic options. This guideline is aimed to assist nuclear medicine physicians in recommending, performing, reporting and interpreting the results of somatostatin receptor (SSTR) PET/CT imaging using68Ga-DOTA-conjugated peptides, as well as18F-DOPA imaging for various neuroendocrine neoplasms.RESULTS & CONCLUSION: The previous procedural guideline by EANM regarding the use PET/CT tumour imaging with68Ga-conjugated peptides has been revised and updated with the relevant and recent literature in the field with contribution of distinguished experts.

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KW - Gallium Radioisotopes

KW - Heterocyclic Compounds, 1-Ring/chemistry

KW - Humans

KW - Image Interpretation, Computer-Assisted

KW - Neuroendocrine Tumors/diagnostic imaging

KW - Peptides/chemistry

KW - Positron Emission Tomography Computed Tomography/methods

KW - Practice Guidelines as Topic

KW - Quality Control

KW - Receptors, Somatostatin/metabolism

KW - Tissue Distribution

UR - https://link.springer.com/article/10.1007%2Fs00259-017-3807-0

U2 - 10.1007/s00259-017-3728-y

DO - 10.1007/s00259-017-3728-y

M3 - Journal article

C2 - 28547177

SN - 1619-7070

VL - 44

SP - 1588

EP - 1601

JO - European Journal of Nuclear Medicine and Molecular Imaging

JF - European Journal of Nuclear Medicine and Molecular Imaging

IS - 9

ER -

Guideline for PET/CT imaging of neuroendocrine neoplasms withGa-DOTA-conjugated somatostatin receptor targeting peptides andF-DOPA

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