[Genetic variations in alcohol dehydrogenase, drinking habits and alcoholism]

J.S. Tolstrup; S. Rasmussen; A. Tybjaerg-Hansen; M. Gronbaek; Børge Nordestgaard

[Genetic variations in alcohol dehydrogenase, drinking habits and alcoholism]

J.S. Tolstrup, S. Rasmussen, A. Tybjaerg-Hansen, M. Gronbaek, Børge Nordestgaard

1 Citation (Scopus)

Abstract

Alcohol is degraded primarily by alcohol dehydrogenase (ADH), and genetic variation that affects the rate of alcohol degradation is found in ADH1B and ADH1C. By genotyping 9,080 white men and women from the general population, we found that men and women with ADH1B slow versus fast alcohol degradation drank approximately 30% more alcohol per week and had a higher risk of everyday and heavy drinking, and of alcoholism. Individuals with ADH1C slow versus fast alcohol degradation had a higher risk of heavy drinking
Udgivelsesdato: 2008/8/25

Original language	Danish
Journal	Ugeskrift for læger
Volume	170
Issue number	35
Pages (from-to)	2672-2675
Number of pages	3
ISSN	0041-5782
Publication status	Published - 2008

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Cite this

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title = "[Genetic variations in alcohol dehydrogenase, drinking habits and alcoholism]",

abstract = "Alcohol is degraded primarily by alcohol dehydrogenase (ADH), and genetic variation that affects the rate of alcohol degradation is found in ADH1B and ADH1C. By genotyping 9,080 white men and women from the general population, we found that men and women with ADH1B slow versus fast alcohol degradation drank approximately 30% more alcohol per week and had a higher risk of everyday and heavy drinking, and of alcoholism. Individuals with ADH1C slow versus fast alcohol degradation had a higher risk of heavy drinking Udgivelsesdato: 2008/8/25",

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year = "2008",

language = "Dansk",

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TY - JOUR

T1 - [Genetic variations in alcohol dehydrogenase, drinking habits and alcoholism]

AU - Tolstrup, J.S.

AU - Rasmussen, S.

AU - Tybjaerg-Hansen, A.

AU - Gronbaek, M.

AU - Nordestgaard, Børge

PY - 2008

Y1 - 2008

N2 - Alcohol is degraded primarily by alcohol dehydrogenase (ADH), and genetic variation that affects the rate of alcohol degradation is found in ADH1B and ADH1C. By genotyping 9,080 white men and women from the general population, we found that men and women with ADH1B slow versus fast alcohol degradation drank approximately 30% more alcohol per week and had a higher risk of everyday and heavy drinking, and of alcoholism. Individuals with ADH1C slow versus fast alcohol degradation had a higher risk of heavy drinking Udgivelsesdato: 2008/8/25

AB - Alcohol is degraded primarily by alcohol dehydrogenase (ADH), and genetic variation that affects the rate of alcohol degradation is found in ADH1B and ADH1C. By genotyping 9,080 white men and women from the general population, we found that men and women with ADH1B slow versus fast alcohol degradation drank approximately 30% more alcohol per week and had a higher risk of everyday and heavy drinking, and of alcoholism. Individuals with ADH1C slow versus fast alcohol degradation had a higher risk of heavy drinking Udgivelsesdato: 2008/8/25

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 170

SP - 2672

EP - 2675

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 35

ER -