Genetic variability at 14 STR loci in the Puna population of north western Argentina

M V Albeza; A Picornell; N Acreche; C Tomas; J A Castro; M M Ramon

doi:10.1007/s00414-001-0268-5

Genetic variability at 14 STR loci in the Puna population of north western Argentina

M V Albeza, A Picornell, N Acreche, C Tomas, J A Castro, M M Ramon

13 Citations (Scopus)

Abstract

Frequency data of the short tandem repeat (STR) loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, HUMTH01, D4S243, D18S535, HUMF13A1 and D12S391 were determined in the Puna population (Andean region from north western Argentina). In this study, 5 out of the 14 loci did not meet Hardy-Weinberg expectations. The excess of homozygotes observed in most of the markers could be due to a Wahlund effect and/or inbreeding. The frequencies were significantly different from those of other compared populations from Europe and America. Forensic parameters indicated that the 14 loci studied in the Puna region are highly discriminating, but the lack of Hardy-Weinberg equilibrium in some of the markers must be taken into account in the application of these results to paternity and forensic casework.

Original language	English
Journal	International Journal of Legal Medicine (Print)
Volume	116
Issue number	3
Pages (from-to)	126-32
Number of pages	6
ISSN	0937-9827
DOIs	https://doi.org/10.1007/s00414-001-0268-5
Publication status	Published - 2002
Externally published	Yes

Access to Document

10.1007/s00414-001-0268-5

Cite this

@article{a8529bf0eda011deba73000ea68e967b,

title = "Genetic variability at 14 STR loci in the Puna population of north western Argentina",

abstract = "Frequency data of the short tandem repeat (STR) loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, HUMTH01, D4S243, D18S535, HUMF13A1 and D12S391 were determined in the Puna population (Andean region from north western Argentina). In this study, 5 out of the 14 loci did not meet Hardy-Weinberg expectations. The excess of homozygotes observed in most of the markers could be due to a Wahlund effect and/or inbreeding. The frequencies were significantly different from those of other compared populations from Europe and America. Forensic parameters indicated that the 14 loci studied in the Puna region are highly discriminating, but the lack of Hardy-Weinberg equilibrium in some of the markers must be taken into account in the application of these results to paternity and forensic casework.",

author = "Albeza, {M V} and A Picornell and N Acreche and C Tomas and Castro, {J A} and Ramon, {M M}",

note = "Keywords: Alleles; Argentina; Gene Frequency; Genetic Markers; Genetic Variation; Heterozygote; Humans; Indians, South American; Tandem Repeat Sequences",

year = "2002",

doi = "10.1007/s00414-001-0268-5",

language = "English",

volume = "116",

pages = "126--32",

journal = "International Journal of Legal Medicine",

issn = "0937-9827",

publisher = "Springer",

number = "3",

}

TY - JOUR

T1 - Genetic variability at 14 STR loci in the Puna population of north western Argentina

AU - Albeza, M V

AU - Picornell, A

AU - Acreche, N

AU - Tomas, C

AU - Castro, J A

AU - Ramon, M M

N1 - Keywords: Alleles; Argentina; Gene Frequency; Genetic Markers; Genetic Variation; Heterozygote; Humans; Indians, South American; Tandem Repeat Sequences

PY - 2002

Y1 - 2002

N2 - Frequency data of the short tandem repeat (STR) loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, HUMTH01, D4S243, D18S535, HUMF13A1 and D12S391 were determined in the Puna population (Andean region from north western Argentina). In this study, 5 out of the 14 loci did not meet Hardy-Weinberg expectations. The excess of homozygotes observed in most of the markers could be due to a Wahlund effect and/or inbreeding. The frequencies were significantly different from those of other compared populations from Europe and America. Forensic parameters indicated that the 14 loci studied in the Puna region are highly discriminating, but the lack of Hardy-Weinberg equilibrium in some of the markers must be taken into account in the application of these results to paternity and forensic casework.

AB - Frequency data of the short tandem repeat (STR) loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, HUMTH01, D4S243, D18S535, HUMF13A1 and D12S391 were determined in the Puna population (Andean region from north western Argentina). In this study, 5 out of the 14 loci did not meet Hardy-Weinberg expectations. The excess of homozygotes observed in most of the markers could be due to a Wahlund effect and/or inbreeding. The frequencies were significantly different from those of other compared populations from Europe and America. Forensic parameters indicated that the 14 loci studied in the Puna region are highly discriminating, but the lack of Hardy-Weinberg equilibrium in some of the markers must be taken into account in the application of these results to paternity and forensic casework.

U2 - 10.1007/s00414-001-0268-5

DO - 10.1007/s00414-001-0268-5

M3 - Journal article

C2 - 12111314

SN - 0937-9827

VL - 116

SP - 126

EP - 132

JO - International Journal of Legal Medicine

JF - International Journal of Legal Medicine

IS - 3

ER -

Genetic variability at 14 STR loci in the Puna population of north western Argentina

Abstract

Access to Document

Fingerprint

Cite this