Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs

Andrew Pakstis; Cemal Gurkan; Mustafa Dogan; Hasan Emin Balkaya; Serkan Dogan; Pavlos I Neophytou; Lotfi Cherni; Sami Boussetta; Houssein Khodjet-El-Khil; Amel Ben Ammar ElGaaied; Nina Mjølsnes Salvo; Kristin  Janssen; Gunn-Hege Olsen; Sibte Hadi; Eida Khalaf Almohammed; Vania Pereira; Ditte Mikkelsen Truelsen; Ozlem Bulbul; Usha Soundararajan; Haseena Rajeevan; J.R. Kidd; KK Kidd

doi:10.1038/s41431-019-0466-6

Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs

Andrew Pakstis, Cemal Gurkan, Mustafa Dogan, Hasan Emin Balkaya, Serkan Dogan, Pavlos I Neophytou, Lotfi Cherni, Sami Boussetta, Houssein Khodjet-El-Khil, Amel Ben Ammar ElGaaied, Nina Mjølsnes Salvo, Kristin Janssen, Gunn-Hege Olsen, Sibte Hadi, Eida Khalaf Almohammed, Vania Pereira, Ditte Mikkelsen Truelsen, Ozlem Bulbul, Usha Soundararajan, Haseena RajeevanJ.R. Kidd, KK Kidd

Section of Forensic Genetics

8 Citations (Scopus)

Abstract

The set of 55 ancestry informative SNPs (AISNPs) originally developed by the Kidd Lab has been studied on a large number of populations and continues to be applied to new population samples. The existing reference database of population samples allows the relationships of new population samples to be inferred on a global level. Analyses show that these autosomal markers constitute one of the better panels of AISNPs. Continuing to build this reference database enhances its value. Because more than half of the 25 ethnic groups recently studied with these AISNPs are from Southwest Asia and the Mediterranean region, we present here various analyses focused on populations from these regions along with selected reference populations from nearby regions where genotype data are available. Many of these ethnic groups have not been previously studied for forensic markers. Data on populations from other world regions have also been added to the database but are not included in these focused analyses. The new population samples added to ALFRED and FROG-kb increase the total to 164 population samples that have been studied for all 55 AISNPs.

Original language	English
Journal	European Journal of Human Genetics
ISSN	1018-4813
DOIs	https://doi.org/10.1038/s41431-019-0466-6
Publication status	Published - 1 Dec 2019

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Pakstis, A., Gurkan, C., Dogan, M., Balkaya, H. E., Dogan, S., Neophytou, P. I., Cherni, L., Boussetta, S., Khodjet-El-Khil, H., ElGaaied, A. B. A., Salvo, N. M., Janssen, K., Olsen, G.-H., Hadi, S., Almohammed, E. K., Pereira, V., Truelsen, D. M., Bulbul, O., Soundararajan, U., ... Kidd, KK. (2019). Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs. European Journal of Human Genetics. https://doi.org/10.1038/s41431-019-0466-6

Pakstis, A, Gurkan, C, Dogan, M, Balkaya, HE, Dogan, S, Neophytou, PI, Cherni, L, Boussetta, S, Khodjet-El-Khil, H, ElGaaied, ABA, Salvo, NM, Janssen, K, Olsen, G-H, Hadi, S, Almohammed, EK, Pereira, V, Truelsen, DM, Bulbul, O, Soundararajan, U, Rajeevan, H, Kidd, JR & Kidd, KK 2019, 'Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs', European Journal of Human Genetics. https://doi.org/10.1038/s41431-019-0466-6

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title = "Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs",

abstract = "The set of 55 ancestry informative SNPs (AISNPs) originally developed by the Kidd Lab has been studied on a large number of populations and continues to be applied to new population samples. The existing reference database of population samples allows the relationships of new population samples to be inferred on a global level. Analyses show that these autosomal markers constitute one of the better panels of AISNPs. Continuing to build this reference database enhances its value. Because more than half of the 25 ethnic groups recently studied with these AISNPs are from Southwest Asia and the Mediterranean region, we present here various analyses focused on populations from these regions along with selected reference populations from nearby regions where genotype data are available. Many of these ethnic groups have not been previously studied for forensic markers. Data on populations from other world regions have also been added to the database but are not included in these focused analyses. The new population samples added to ALFRED and FROG-kb increase the total to 164 population samples that have been studied for all 55 AISNPs.",

author = "Andrew Pakstis and Cemal Gurkan and Mustafa Dogan and Balkaya, {Hasan Emin} and Serkan Dogan and Neophytou, {Pavlos I} and Lotfi Cherni and Sami Boussetta and Houssein Khodjet-El-Khil and ElGaaied, {Amel Ben Ammar} and Salvo, {Nina Mj{\o}lsnes} and Kristin Janssen and Gunn-Hege Olsen and Sibte Hadi and Almohammed, {Eida Khalaf} and Vania Pereira and Truelsen, {Ditte Mikkelsen} and Ozlem Bulbul and Usha Soundararajan and Haseena Rajeevan and J.R. Kidd and KK Kidd",

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T1 - Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs

AU - Pakstis, Andrew

AU - Gurkan, Cemal

AU - Dogan, Mustafa

AU - Balkaya, Hasan Emin

AU - Dogan, Serkan

AU - Neophytou, Pavlos I

AU - Cherni, Lotfi

AU - Boussetta, Sami

AU - Khodjet-El-Khil, Houssein

AU - ElGaaied, Amel Ben Ammar

AU - Salvo, Nina Mjølsnes

AU - Janssen, Kristin

AU - Olsen, Gunn-Hege

AU - Hadi, Sibte

AU - Almohammed, Eida Khalaf

AU - Pereira, Vania

AU - Truelsen, Ditte Mikkelsen

AU - Bulbul, Ozlem

AU - Soundararajan, Usha

AU - Rajeevan, Haseena

AU - Kidd, J.R.

AU - Kidd, KK

PY - 2019/12/1

Y1 - 2019/12/1

N2 - The set of 55 ancestry informative SNPs (AISNPs) originally developed by the Kidd Lab has been studied on a large number of populations and continues to be applied to new population samples. The existing reference database of population samples allows the relationships of new population samples to be inferred on a global level. Analyses show that these autosomal markers constitute one of the better panels of AISNPs. Continuing to build this reference database enhances its value. Because more than half of the 25 ethnic groups recently studied with these AISNPs are from Southwest Asia and the Mediterranean region, we present here various analyses focused on populations from these regions along with selected reference populations from nearby regions where genotype data are available. Many of these ethnic groups have not been previously studied for forensic markers. Data on populations from other world regions have also been added to the database but are not included in these focused analyses. The new population samples added to ALFRED and FROG-kb increase the total to 164 population samples that have been studied for all 55 AISNPs.

AB - The set of 55 ancestry informative SNPs (AISNPs) originally developed by the Kidd Lab has been studied on a large number of populations and continues to be applied to new population samples. The existing reference database of population samples allows the relationships of new population samples to be inferred on a global level. Analyses show that these autosomal markers constitute one of the better panels of AISNPs. Continuing to build this reference database enhances its value. Because more than half of the 25 ethnic groups recently studied with these AISNPs are from Southwest Asia and the Mediterranean region, we present here various analyses focused on populations from these regions along with selected reference populations from nearby regions where genotype data are available. Many of these ethnic groups have not been previously studied for forensic markers. Data on populations from other world regions have also been added to the database but are not included in these focused analyses. The new population samples added to ALFRED and FROG-kb increase the total to 164 population samples that have been studied for all 55 AISNPs.

U2 - 10.1038/s41431-019-0466-6

DO - 10.1038/s41431-019-0466-6

M3 - Journal article

C2 - 31285530

SN - 1018-4813

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

ER -

Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs

Abstract

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