Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

James J. Lee; Robbee Wedow; Aysu Okbay; Edward Kong; Omeed Maghzian; Meghan Zacher; null Tuan Anh Nguyen-Viet; Peter Bowers; Julia Sidorenko; Richard Karlsson Linner; Mark Alan Fontana; Tushar Kundu; Chanwook Lee; Hui Li; Ruoxi Li; Rebecca Royer; Pascal N. Timshel; Raymond K. Walters; Emily A. Willoughby; Loic Yengo; Maris Alver; Yanchun Bao; David W. Clark; Felix R. Day; Nicholas A. Furlotte; Peter K. Joshi; Kathryn E. Kemper; Aaron Kleinman; Claudia Langenberg; Reedik Magi; Joey W. Trampush; Shefali Setia Verma; Yang Wu; Max Lam; Jing Hua Zhao; Zhili Zheng; Jason D. Boardman; Harry Campbell; Jeremy Freese; Kathleen Mullan Harris; Caroline Hayward; Pamela Herd; Meena Kumari; Todd Lencz; Jian'an Luan; Anil K. Malhotra; Andres Metspalu; Lili Milani; Ken K. Ong; John R. B. Perry; David J. Porteous; Marylyn D. Ritchie; Melissa C. Smart; Blair H. Smith; Joyce Y. Tung; Nicholas J. Wareham; James F. Wilson; Jonathan P. Beauchamp; Dalton C. Conley; Tonu Esko; Steven F. Lehrer; Patrik K. E. Magnusson; Sven Oskarsson; Tune H. Pers; Matthew R. Robinson; Kevin Thom; Chelsea Watson; Christopher F. Chabris; Michelle N. Meyer; David I. Laibson; Jian Yang; Magnus Johannesson; Philipp D. Koellinger; Patrick Turley; Peter M. Visscher; Daniel J. Benjamin; David Cesarini; Thorkild I.A. Sørensen

doi:10.1038/s41588-018-0147-3

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

James J. Lee, Robbee Wedow, Aysu Okbay, Edward Kong, Omeed Maghzian, Meghan Zacher, Tuan Anh Nguyen-Viet, Peter Bowers, Julia Sidorenko, Richard Karlsson Linner, Mark Alan Fontana, Tushar Kundu, Chanwook Lee, Hui Li, Ruoxi Li, Rebecca Royer, Pascal N. Timshel, Raymond K. Walters, Emily A. Willoughby, Loic YengoMaris Alver, Yanchun Bao, David W. Clark, Felix R. Day, Nicholas A. Furlotte, Peter K. Joshi, Kathryn E. Kemper, Aaron Kleinman, Claudia Langenberg, Reedik Magi, Joey W. Trampush, Shefali Setia Verma, Yang Wu, Max Lam, Jing Hua Zhao, Zhili Zheng, Jason D. Boardman, Harry Campbell, Jeremy Freese, Kathleen Mullan Harris, Caroline Hayward, Pamela Herd, Meena Kumari, Todd Lencz, Jian'an Luan, Anil K. Malhotra, Andres Metspalu, Lili Milani, Ken K. Ong, John R. B. Perry, David J. Porteous, Marylyn D. Ritchie, Melissa C. Smart, Blair H. Smith, Joyce Y. Tung, Nicholas J. Wareham, James F. Wilson, Jonathan P. Beauchamp, Dalton C. Conley, Tonu Esko, Steven F. Lehrer, Patrik K. E. Magnusson, Sven Oskarsson, Tune H. Pers, Matthew R. Robinson, Kevin Thom, Chelsea Watson, Christopher F. Chabris, Michelle N. Meyer, David I. Laibson, Jian Yang, Magnus Johannesson, Philipp D. Koellinger, Patrick Turley, Peter M. Visscher, Daniel J. Benjamin, David Cesarini, Thorkild I.A. Sørensen

Department of Public Health

474 Citations (Scopus)

Original language	English
Journal	Nature Genetics
Volume	50
Issue number	8
Pages (from-to)	1112-+
ISSN	1061-4036
DOIs	https://doi.org/10.1038/s41588-018-0147-3
Publication status	Published - 1 Aug 2018

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Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Tuan Anh Nguyen-Viet, Bowers, P., Sidorenko, J., Linner, R. K., Fontana, M. A., Kundu, T., Lee, C., Li, H., Li, R., Royer, R., Timshel, P. N., Walters, R. K., Willoughby, E. A., ... Sørensen, T. I. A. (2018). Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nature Genetics, 50(8), 1112-+. https://doi.org/10.1038/s41588-018-0147-3

Lee, JJ, Wedow, R, Okbay, A, Kong, E, Maghzian, O, Zacher, M, Tuan Anh Nguyen-Viet, Bowers, P, Sidorenko, J, Linner, RK, Fontana, MA, Kundu, T, Lee, C, Li, H, Li, R, Royer, R, Timshel, PN, Walters, RK, Willoughby, EA, Yengo, L, Alver, M, Bao, Y, Clark, DW, Day, FR, Furlotte, NA, Joshi, PK, Kemper, KE, Kleinman, A, Langenberg, C, Magi, R, Trampush, JW, Verma, SS, Wu, Y, Lam, M, Zhao, JH, Zheng, Z, Boardman, JD, Campbell, H, Freese, J, Harris, KM, Hayward, C, Herd, P, Kumari, M, Lencz, T, Luan, J, Malhotra, AK, Metspalu, A, Milani, L, Ong, KK, Perry, JRB, Porteous, DJ, Ritchie, MD, Smart, MC, Smith, BH, Tung, JY, Wareham, NJ, Wilson, JF, Beauchamp, JP, Conley, DC, Esko, T, Lehrer, SF, Magnusson, PKE, Oskarsson, S, Pers, TH, Robinson, MR, Thom, K, Watson, C, Chabris, CF, Meyer, MN, Laibson, DI, Yang, J, Johannesson, M, Koellinger, PD, Turley, P, Visscher, PM, Benjamin, DJ, Cesarini, D & Sørensen, TIA 2018, 'Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals', Nature Genetics, vol. 50, no. 8, pp. 1112-+. https://doi.org/10.1038/s41588-018-0147-3

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author = "Lee, {James J.} and Robbee Wedow and Aysu Okbay and Edward Kong and Omeed Maghzian and Meghan Zacher and {Tuan Anh Nguyen-Viet} and Peter Bowers and Julia Sidorenko and Linner, {Richard Karlsson} and Fontana, {Mark Alan} and Tushar Kundu and Chanwook Lee and Hui Li and Ruoxi Li and Rebecca Royer and Timshel, {Pascal N.} and Walters, {Raymond K.} and Willoughby, {Emily A.} and Loic Yengo and Maris Alver and Yanchun Bao and Clark, {David W.} and Day, {Felix R.} and Furlotte, {Nicholas A.} and Joshi, {Peter K.} and Kemper, {Kathryn E.} and Aaron Kleinman and Claudia Langenberg and Reedik Magi and Trampush, {Joey W.} and Verma, {Shefali Setia} and Yang Wu and Max Lam and Zhao, {Jing Hua} and Zhili Zheng and Boardman, {Jason D.} and Harry Campbell and Jeremy Freese and Harris, {Kathleen Mullan} and Caroline Hayward and Pamela Herd and Meena Kumari and Todd Lencz and Jian'an Luan and Malhotra, {Anil K.} and Andres Metspalu and Lili Milani and Ong, {Ken K.} and Perry, {John R. B.} and Porteous, {David J.} and Ritchie, {Marylyn D.} and Smart, {Melissa C.} and Smith, {Blair H.} and Tung, {Joyce Y.} and Wareham, {Nicholas J.} and Wilson, {James F.} and Beauchamp, {Jonathan P.} and Conley, {Dalton C.} and Tonu Esko and Lehrer, {Steven F.} and Magnusson, {Patrik K. E.} and Sven Oskarsson and Pers, {Tune H.} and Robinson, {Matthew R.} and Kevin Thom and Chelsea Watson and Chabris, {Christopher F.} and Meyer, {Michelle N.} and Laibson, {David I.} and Jian Yang and Magnus Johannesson and Koellinger, {Philipp D.} and Patrick Turley and Visscher, {Peter M.} and Benjamin, {Daniel J.} and David Cesarini and S{\o}rensen, {Thorkild I.A.}",

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AU - Lee, James J.

AU - Wedow, Robbee

AU - Okbay, Aysu

AU - Kong, Edward

AU - Maghzian, Omeed

AU - Zacher, Meghan

AU - Tuan Anh Nguyen-Viet, null

AU - Bowers, Peter

AU - Sidorenko, Julia

AU - Linner, Richard Karlsson

AU - Fontana, Mark Alan

AU - Kundu, Tushar

AU - Lee, Chanwook

AU - Li, Hui

AU - Li, Ruoxi

AU - Royer, Rebecca

AU - Timshel, Pascal N.

AU - Walters, Raymond K.

AU - Willoughby, Emily A.

AU - Yengo, Loic

AU - Alver, Maris

AU - Bao, Yanchun

AU - Clark, David W.

AU - Day, Felix R.

AU - Furlotte, Nicholas A.

AU - Joshi, Peter K.

AU - Kemper, Kathryn E.

AU - Kleinman, Aaron

AU - Langenberg, Claudia

AU - Magi, Reedik

AU - Trampush, Joey W.

AU - Verma, Shefali Setia

AU - Wu, Yang

AU - Lam, Max

AU - Zhao, Jing Hua

AU - Zheng, Zhili

AU - Boardman, Jason D.

AU - Campbell, Harry

AU - Freese, Jeremy

AU - Harris, Kathleen Mullan

AU - Hayward, Caroline

AU - Herd, Pamela

AU - Kumari, Meena

AU - Lencz, Todd

AU - Luan, Jian'an

AU - Malhotra, Anil K.

AU - Metspalu, Andres

AU - Milani, Lili

AU - Ong, Ken K.

AU - Perry, John R. B.

AU - Porteous, David J.

AU - Ritchie, Marylyn D.

AU - Smart, Melissa C.

AU - Smith, Blair H.

AU - Tung, Joyce Y.

AU - Wareham, Nicholas J.

AU - Wilson, James F.

AU - Beauchamp, Jonathan P.

AU - Conley, Dalton C.

AU - Esko, Tonu

AU - Lehrer, Steven F.

AU - Magnusson, Patrik K. E.

AU - Oskarsson, Sven

AU - Pers, Tune H.

AU - Robinson, Matthew R.

AU - Thom, Kevin

AU - Watson, Chelsea

AU - Chabris, Christopher F.

AU - Meyer, Michelle N.

AU - Laibson, David I.

AU - Yang, Jian

AU - Johannesson, Magnus

AU - Koellinger, Philipp D.

AU - Turley, Patrick

AU - Visscher, Peter M.

AU - Benjamin, Daniel J.

AU - Cesarini, David

AU - Sørensen, Thorkild I.A.

PY - 2018/8/1

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U2 - 10.1038/s41588-018-0147-3

DO - 10.1038/s41588-018-0147-3

M3 - Journal article

C2 - 30038396

SN - 1061-4036

VL - 50

SP - 1112-+

JO - Nature Genetics

JF - Nature Genetics

IS - 8

ER -

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

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