Functional in vitro studies of recombinant human immunoglobulin G and immunoglobulin A anti-D

Leif Kofoed Nielsen, Trine Hefsgaard Green, Lars Norderhaug, Inger Sandlie, Morten Hanefeld Dziegiel

    11 Citations (Scopus)

    Abstract

    The use of anti-D purified from human serum to prevent hemolytic disease of the fetus and newborn due to D is well established. Owing to supply and safety reasons, however, an unlimited and non-plasma-derived source of antibodies for Rhesus prophylaxis is needed.
    Original languageEnglish
    JournalTransfusion
    Volume47
    Issue number2
    Pages (from-to)306-15
    Number of pages10
    ISSN0041-1132
    DOIs
    Publication statusPublished - Feb 2007

    Keywords

    • Animals
    • Antibody Specificity
    • CHO Cells
    • Cricetinae
    • Cricetulus
    • Gene Expression
    • Humans
    • Immunoglobulin A
    • Immunoglobulin G
    • Recombinant Proteins
    • Respiratory Burst
    • Rh-Hr Blood-Group System
    • Transfection

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