FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness

Sofia I I Kring; Claus Holst; Esther Zimmermann; Tine Jess; Tina Berentzen; Søren Toubro; Torben Hansen; Arne Astrup; Oluf Pedersen; Thorkild I A Sørensen

doi:10.1371/journal.pone.0002958

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness

Sofia I I Kring, Claus Holst, Esther Zimmermann, Tine Jess, Tina Berentzen, Søren Toubro, Torben Hansen, Arne Astrup, Oluf Pedersen, Thorkild I A Sørensen

62 Citations (Scopus)

Abstract

A common single nucleotide polymorphism (SNP) of FTO (rs9939609, T/A) is associated with total body fatness. We investigated the association of this SNP with abdominal and peripheral fatness and obesity-related metabolic traits in middle-aged men through a broad range of fatness present already in adolescence.

Original language	English
Journal	PLoS ONE
Volume	3
Issue number	8
Pages (from-to)	e2958
Number of pages	7
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0002958
Publication status	Published - 2008

Keywords

Adipose Tissue
Adult
Body Mass Index
Cholesterol, HDL
Denmark
Genotype
Health Surveys
Humans
Male
Middle Aged
Obesity
Overweight
Phenotype
Polymorphism, Single Nucleotide
Prevalence
Proteins
Retrospective Studies

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1371/journal.pone.0002958

http://www.plosone.org/static/information.action

Cite this

@article{48f65cb0a1c411ddb6ae000ea68e967b,

title = "FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness",

abstract = "A common single nucleotide polymorphism (SNP) of FTO (rs9939609, T/A) is associated with total body fatness. We investigated the association of this SNP with abdominal and peripheral fatness and obesity-related metabolic traits in middle-aged men through a broad range of fatness present already in adolescence.",

keywords = "Adipose Tissue, Adult, Body Mass Index, Cholesterol, HDL, Denmark, Genotype, Health Surveys, Humans, Male, Middle Aged, Obesity, Overweight, Phenotype, Polymorphism, Single Nucleotide, Prevalence, Proteins, Retrospective Studies",

author = "Kring, {Sofia I I} and Claus Holst and Esther Zimmermann and Tine Jess and Tina Berentzen and S{\o}ren Toubro and Torben Hansen and Arne Astrup and Oluf Pedersen and S{\o}rensen, {Thorkild I A}",

year = "2008",

doi = "10.1371/journal.pone.0002958",

language = "English",

volume = "3",

pages = "e2958",

journal = "PLoS Computational Biology",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "8",

}

TY - JOUR

T1 - FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness

AU - Kring, Sofia I I

AU - Holst, Claus

AU - Zimmermann, Esther

AU - Jess, Tine

AU - Berentzen, Tina

AU - Toubro, Søren

AU - Hansen, Torben

AU - Astrup, Arne

AU - Pedersen, Oluf

AU - Sørensen, Thorkild I A

PY - 2008

Y1 - 2008

N2 - A common single nucleotide polymorphism (SNP) of FTO (rs9939609, T/A) is associated with total body fatness. We investigated the association of this SNP with abdominal and peripheral fatness and obesity-related metabolic traits in middle-aged men through a broad range of fatness present already in adolescence.

AB - A common single nucleotide polymorphism (SNP) of FTO (rs9939609, T/A) is associated with total body fatness. We investigated the association of this SNP with abdominal and peripheral fatness and obesity-related metabolic traits in middle-aged men through a broad range of fatness present already in adolescence.

KW - Adipose Tissue

KW - Adult

KW - Body Mass Index

KW - Cholesterol, HDL

KW - Denmark

KW - Genotype

KW - Health Surveys

KW - Humans

KW - Male

KW - Middle Aged

KW - Obesity

KW - Overweight

KW - Phenotype

KW - Polymorphism, Single Nucleotide

KW - Prevalence

KW - Proteins

KW - Retrospective Studies

U2 - 10.1371/journal.pone.0002958

DO - 10.1371/journal.pone.0002958

M3 - Journal article

C2 - 18698412

SN - 1932-6203

VL - 3

SP - e2958

JO - PLoS Computational Biology

JF - PLoS Computational Biology

IS - 8

ER -

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this