From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries

Sophie R. Beeren; Michael Pittelkow; Jeremy K. M. Sanders

From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries

Sophie R. Beeren, Michael Pittelkow, Jeremy K. M. Sanders

Department of Chemistry

31 Citations (Scopus)

Abstract

Thermodynamic control over kinetically-trapped mixtures of hydrazone-based macrocycles is achieved by addition of an aromatic monohydrazide to generate dynamic combinatorial libraries (DCLs) of linear and macrocyclic oligomers.

Original language	English
Journal	Chemical Communications
Volume	47
Pages (from-to)	7359-7361
ISSN	1359-7345
Publication status	Published - 14 Jul 2011

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title = "From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries",

abstract = "Thermodynamic control over kinetically-trapped mixtures of hydrazone-based macrocycles is achieved by addition of an aromatic monohydrazide to generate dynamic combinatorial libraries (DCLs) of linear and macrocyclic oligomers.",

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AU - Beeren, Sophie R.

AU - Pittelkow, Michael

AU - Sanders, Jeremy K. M.

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Y1 - 2011/7/14

N2 - Thermodynamic control over kinetically-trapped mixtures of hydrazone-based macrocycles is achieved by addition of an aromatic monohydrazide to generate dynamic combinatorial libraries (DCLs) of linear and macrocyclic oligomers.

AB - Thermodynamic control over kinetically-trapped mixtures of hydrazone-based macrocycles is achieved by addition of an aromatic monohydrazide to generate dynamic combinatorial libraries (DCLs) of linear and macrocyclic oligomers.

M3 - Journal article

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VL - 47

SP - 7359

EP - 7361

JO - Chemical Communications

JF - Chemical Communications

ER -

From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries

Abstract

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