Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

P V Højberg; Tina Vilsbøll; Pär-Ola Mikael Zander; F K Knop; T Krarup; Anders Vølund; Jens Møller Holst; S Madsbad

doi:10.1111/j.1464-5491.2008.02579.x

Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

P V Højberg, Tina Vilsbøll, Pär-Ola Mikael Zander, F K Knop, T Krarup, Anders Vølund, Jens Møller Holst, S Madsbad

Department of Clinical Medicine

40 Citations (Scopus)

Abstract

The aim of the present study was to investigate whether 4 weeks of near-normalization of blood glucose (BG) improves incretin hormone secretion and pancreatic B-cell function during a mixed meal.

Original language	English
Journal	Diabetic Medicine
Volume	25
Issue number	11
Pages (from-to)	1268-75
Number of pages	8
ISSN	0742-3071
DOIs	https://doi.org/10.1111/j.1464-5491.2008.02579.x https://doi.org/10.1111/j.1464-5491.2008.02579.x
Publication status	Published - 1 Nov 2008

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Højberg, P. V., Vilsbøll, T., Zander, P-O. M., Knop, F. K., Krarup, T., Vølund, A., Holst, J. M., & Madsbad, S. (2008). Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes. Diabetic Medicine, 25(11), 1268-75. https://doi.org/10.1111/j.1464-5491.2008.02579.x, https://doi.org/10.1111/j.1464-5491.2008.02579.x

Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes. / Højberg, P V; Vilsbøll, Tina; Zander, Pär-Ola Mikael et al.

In: Diabetic Medicine, Vol. 25, No. 11, 01.11.2008, p. 1268-75.

Research output: Contribution to journal › Journal article › Research › peer-review

Højberg, PV, Vilsbøll, T, Zander, P-OM, Knop, FK, Krarup, T, Vølund, A, Holst, JM & Madsbad, S 2008, 'Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes', Diabetic Medicine, vol. 25, no. 11, pp. 1268-75. https://doi.org/10.1111/j.1464-5491.2008.02579.x, https://doi.org/10.1111/j.1464-5491.2008.02579.x

Højberg PV, Vilsbøll T, Zander P-OM, Knop FK, Krarup T, Vølund A et al. Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes. Diabetic Medicine. 2008 Nov 1;25(11):1268-75. doi: 10.1111/j.1464-5491.2008.02579.x, http://dx.doi.org/10.1111/j.1464-5491.2008.02579.x

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Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

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