Fluid management in acute kidney injury

TY - JOUR

T1 - Fluid management in acute kidney injury

AU - Perner, Anders

AU - Prowle, John

AU - Joannidis, Michael

AU - Young, Paul

AU - Hjortrup, Peter B

AU - Pettilä, Ville

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Acute kidney injury (AKI) and fluids are closely linked through oliguria, which is a marker of the former and a trigger for administration of the latter. Recent progress in this field has challenged the physiological and clinical rational of using oliguria as a trigger for the administration of fluid and brought attention to the delicate balance between benefits and harms of different aspects of fluid management in critically ill patients, in particular those with AKI. This narrative review addresses various aspects of fluid management in AKI outlining physiological aspects, the effects of crystalloids and colloids on kidney function and the effect of various resuscitation and de-resuscitation strategies on the course and outcome of AKI.

AB - Acute kidney injury (AKI) and fluids are closely linked through oliguria, which is a marker of the former and a trigger for administration of the latter. Recent progress in this field has challenged the physiological and clinical rational of using oliguria as a trigger for the administration of fluid and brought attention to the delicate balance between benefits and harms of different aspects of fluid management in critically ill patients, in particular those with AKI. This narrative review addresses various aspects of fluid management in AKI outlining physiological aspects, the effects of crystalloids and colloids on kidney function and the effect of various resuscitation and de-resuscitation strategies on the course and outcome of AKI.

U2 - 10.1007/s00134-017-4817-x

DO - 10.1007/s00134-017-4817-x

M3 - Review

C2 - 28470347

SN - 0935-1701

VL - 43

SP - 807

EP - 815

JO - European Journal of Intensive Care Medicine

JF - European Journal of Intensive Care Medicine

IS - 6

ER -