TY - JOUR
T1 - Flat affect and social functioning
T2 - A 10year follow-up study of first episode psychosis patients
AU - Evensen, Julie
AU - Røssberg, Jan Ivar
AU - Barder, Helene
AU - Haahr, Ulrik
AU - Hegelstad, Wenche Ten Velden
AU - Joa, Inge
AU - Johannessen, Jan Olav
AU - Larsen, Tor Ketil
AU - Melle, Ingrid
AU - Opjordsmoen, Stein
AU - Rund, Bjørn Rishovd
AU - Simonsen, Erik
AU - Vaglum, Per
AU - McGlashan, Thomas
AU - Friis, Svein
N1 - Copyright © 2012 Elsevier B.V. All rights reserved.
PY - 2012/8
Y1 - 2012/8
N2 - Background: Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking. Objective: The aim of this study was to follow the symptom development of flat affect (FA), over a 10. year follow-up period, with focus on prevalence, predictors and outcome factors including social functioning. Methods: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10. year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10. years. Patients were grouped as having never-present, improving, deteriorating, fluctuating or enduring FA. The groups were compared on baseline variables, variables at 10. year follow-up, and social functioning throughout the follow-up period. Results: Twenty nine percent never displayed FA, 66% had improving, deteriorating or fluctuating FA, while 5% of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring, fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning over the 10. year period. Conclusions: FA is expressed at some point of time in the majority of FEP patients in a 10. year follow-up period, and appears more fluctuant than expected from the relevant literature. FA is associated with poorer outcome after 10. years, and enduring FA to poorer social function at all points of assessment.
AB - Background: Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking. Objective: The aim of this study was to follow the symptom development of flat affect (FA), over a 10. year follow-up period, with focus on prevalence, predictors and outcome factors including social functioning. Methods: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10. year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10. years. Patients were grouped as having never-present, improving, deteriorating, fluctuating or enduring FA. The groups were compared on baseline variables, variables at 10. year follow-up, and social functioning throughout the follow-up period. Results: Twenty nine percent never displayed FA, 66% had improving, deteriorating or fluctuating FA, while 5% of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring, fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning over the 10. year period. Conclusions: FA is expressed at some point of time in the majority of FEP patients in a 10. year follow-up period, and appears more fluctuant than expected from the relevant literature. FA is associated with poorer outcome after 10. years, and enduring FA to poorer social function at all points of assessment.
U2 - 10.1016/j.schres.2012.04.019
DO - 10.1016/j.schres.2012.04.019
M3 - Journal article
C2 - 22627124
SN - 0920-9964
VL - 139
SP - 99
EP - 104
JO - Schizophrenia Research
JF - Schizophrenia Research
IS - 1-3
ER -