First experiences from Copenhagen with paediatric single photon emission computed tomography/computed tomography

Julie Bjerglund Andersen; Jann Mortensen; Birthe Højlund Bech; Liselotte Højgaard; Lise Borgwardt; Julie Bjerglund Andersen

doi:10.1097/mnm.0b013e328342823d

First experiences from Copenhagen with paediatric single photon emission computed tomography/computed tomography

Julie Bjerglund Andersen, Jann Mortensen, Birthe Højlund Bech, Liselotte Højgaard, Lise Borgwardt, Julie Bjerglund Andersen

7 Citations (Scopus)

Abstract

OBJECTIVE: This study evaluates the diagnostic value of single photon emission computed tomographic (SPECT)/multislice computed tomographic (MSCT) fusion images compared with planar scintigraphy in children. METHODS: Fifteen children [eight girls, mean age 13 years (range 2-17 years)] who were examined in the SPECT/16-MSCT scanner at the Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet were included. The studies and clinical indications were eight ^99mTc-hydroxymethane diphosphonate bone scintigraphies (three bone abnormalities, three osteomyelitis, two bone tumours), one bone scintigraphy combined with ¹¹¹In-labelled leukocyte study (osteomyelitis), three ¹²³I-meta-iodobenzylguanidine scintigraphies (neuroblastoma), three ¹¹¹In-octreotide scintigraphies (two carcinoid tumours, one Langerhans cell histiocytosis) and one ^99mTc-dimercaptosuccinic acid scintigraphy (suspected renal transplant infarction). At the evaluation of the planar scans, the decision to perform a SPECT/16-MSCT scan was taken. A specialist in nuclear medicine read the SPECT scans and the CT scans were, if performed as high resolution or when in doubt, read by the specialist in radiology, followed by a simultaneous reading. We categorized the additional information gained from the SPECT/MSCT scan into three groups: (i) structural information gained from the CT scan, (ii) additional nuclear medicine information gained from the SPECT scan and (iii) information used for biopsy guidance. Use of a CT scan of diagnostic quality was only allowed (n=1) after referral from the clinicians, and read in collaboration with the specialist in radiology. RESULTS: Fourteen of the 15 planar scans gained additional structural information from SPECT/CT. Twelve of 15 planar scans gained additional nuclear medicine information. Six studies gained specific information for biopsy guidance. CONCLUSION: SPECT/CT provided additional information in all cases. SPECT/CT in children seems to be a most valuable tool and it increases the certainty of the diagnostic work-up.

Original language	English
Journal	Nuclear Medicine Communications
Volume	32
Issue number	5
Pages (from-to)	356-362
ISSN	0143-3636
DOIs	https://doi.org/10.1097/mnm.0b013e328342823d
Publication status	Published - May 2011

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10.1097/mnm.0b013e328342823d

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@article{b8c79bfdebd1477aac2751810963f628,

title = "First experiences from Copenhagen with paediatric single photon emission computed tomography/computed tomography",

abstract = "OBJECTIVE: This study evaluates the diagnostic value of single photon emission computed tomographic (SPECT)/multislice computed tomographic (MSCT) fusion images compared with planar scintigraphy in children. METHODS: Fifteen children [eight girls, mean age 13 years (range 2-17 years)] who were examined in the SPECT/16-MSCT scanner at the Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet were included. The studies and clinical indications were eight 99mTc-hydroxymethane diphosphonate bone scintigraphies (three bone abnormalities, three osteomyelitis, two bone tumours), one bone scintigraphy combined with 111In-labelled leukocyte study (osteomyelitis), three 123I-meta-iodobenzylguanidine scintigraphies (neuroblastoma), three 111In-octreotide scintigraphies (two carcinoid tumours, one Langerhans cell histiocytosis) and one 99mTc-dimercaptosuccinic acid scintigraphy (suspected renal transplant infarction). At the evaluation of the planar scans, the decision to perform a SPECT/16-MSCT scan was taken. A specialist in nuclear medicine read the SPECT scans and the CT scans were, if performed as high resolution or when in doubt, read by the specialist in radiology, followed by a simultaneous reading. We categorized the additional information gained from the SPECT/MSCT scan into three groups: (i) structural information gained from the CT scan, (ii) additional nuclear medicine information gained from the SPECT scan and (iii) information used for biopsy guidance. Use of a CT scan of diagnostic quality was only allowed (n=1) after referral from the clinicians, and read in collaboration with the specialist in radiology. RESULTS: Fourteen of the 15 planar scans gained additional structural information from SPECT/CT. Twelve of 15 planar scans gained additional nuclear medicine information. Six studies gained specific information for biopsy guidance. CONCLUSION: SPECT/CT provided additional information in all cases. SPECT/CT in children seems to be a most valuable tool and it increases the certainty of the diagnostic work-up.",

author = "Andersen, {Julie Bjerglund} and Jann Mortensen and Bech, {Birthe H{\o}jlund} and Liselotte H{\o}jgaard and Lise Borgwardt and Andersen, {Julie Bjerglund}",

year = "2011",

month = may,

doi = "10.1097/mnm.0b013e328342823d",

language = "English",

volume = "32",

pages = "356--362",

journal = "Nuclear Medicine Communications",

issn = "0143-3636",

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T1 - First experiences from Copenhagen with paediatric single photon emission computed tomography/computed tomography

AU - Andersen, Julie Bjerglund

AU - Mortensen, Jann

AU - Bech, Birthe Højlund

AU - Højgaard, Liselotte

AU - Borgwardt, Lise

AU - Andersen, Julie Bjerglund

PY - 2011/5

Y1 - 2011/5

N2 - OBJECTIVE: This study evaluates the diagnostic value of single photon emission computed tomographic (SPECT)/multislice computed tomographic (MSCT) fusion images compared with planar scintigraphy in children. METHODS: Fifteen children [eight girls, mean age 13 years (range 2-17 years)] who were examined in the SPECT/16-MSCT scanner at the Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet were included. The studies and clinical indications were eight 99mTc-hydroxymethane diphosphonate bone scintigraphies (three bone abnormalities, three osteomyelitis, two bone tumours), one bone scintigraphy combined with 111In-labelled leukocyte study (osteomyelitis), three 123I-meta-iodobenzylguanidine scintigraphies (neuroblastoma), three 111In-octreotide scintigraphies (two carcinoid tumours, one Langerhans cell histiocytosis) and one 99mTc-dimercaptosuccinic acid scintigraphy (suspected renal transplant infarction). At the evaluation of the planar scans, the decision to perform a SPECT/16-MSCT scan was taken. A specialist in nuclear medicine read the SPECT scans and the CT scans were, if performed as high resolution or when in doubt, read by the specialist in radiology, followed by a simultaneous reading. We categorized the additional information gained from the SPECT/MSCT scan into three groups: (i) structural information gained from the CT scan, (ii) additional nuclear medicine information gained from the SPECT scan and (iii) information used for biopsy guidance. Use of a CT scan of diagnostic quality was only allowed (n=1) after referral from the clinicians, and read in collaboration with the specialist in radiology. RESULTS: Fourteen of the 15 planar scans gained additional structural information from SPECT/CT. Twelve of 15 planar scans gained additional nuclear medicine information. Six studies gained specific information for biopsy guidance. CONCLUSION: SPECT/CT provided additional information in all cases. SPECT/CT in children seems to be a most valuable tool and it increases the certainty of the diagnostic work-up.

AB - OBJECTIVE: This study evaluates the diagnostic value of single photon emission computed tomographic (SPECT)/multislice computed tomographic (MSCT) fusion images compared with planar scintigraphy in children. METHODS: Fifteen children [eight girls, mean age 13 years (range 2-17 years)] who were examined in the SPECT/16-MSCT scanner at the Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet were included. The studies and clinical indications were eight 99mTc-hydroxymethane diphosphonate bone scintigraphies (three bone abnormalities, three osteomyelitis, two bone tumours), one bone scintigraphy combined with 111In-labelled leukocyte study (osteomyelitis), three 123I-meta-iodobenzylguanidine scintigraphies (neuroblastoma), three 111In-octreotide scintigraphies (two carcinoid tumours, one Langerhans cell histiocytosis) and one 99mTc-dimercaptosuccinic acid scintigraphy (suspected renal transplant infarction). At the evaluation of the planar scans, the decision to perform a SPECT/16-MSCT scan was taken. A specialist in nuclear medicine read the SPECT scans and the CT scans were, if performed as high resolution or when in doubt, read by the specialist in radiology, followed by a simultaneous reading. We categorized the additional information gained from the SPECT/MSCT scan into three groups: (i) structural information gained from the CT scan, (ii) additional nuclear medicine information gained from the SPECT scan and (iii) information used for biopsy guidance. Use of a CT scan of diagnostic quality was only allowed (n=1) after referral from the clinicians, and read in collaboration with the specialist in radiology. RESULTS: Fourteen of the 15 planar scans gained additional structural information from SPECT/CT. Twelve of 15 planar scans gained additional nuclear medicine information. Six studies gained specific information for biopsy guidance. CONCLUSION: SPECT/CT provided additional information in all cases. SPECT/CT in children seems to be a most valuable tool and it increases the certainty of the diagnostic work-up.

U2 - 10.1097/mnm.0b013e328342823d

DO - 10.1097/mnm.0b013e328342823d

M3 - Journal article

C2 - 21383641

SN - 0143-3636

VL - 32

SP - 356

EP - 362

JO - Nuclear Medicine Communications

JF - Nuclear Medicine Communications

IS - 5

ER -

First experiences from Copenhagen with paediatric single photon emission computed tomography/computed tomography

Abstract

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