Fatal Septicemia Linked to Transmission of MRSA Clonal Complex 398 in Hospital and Nursing Home, Denmark

Rikke Thoft Nielsen; Michael Kemp; Anette Holm; Marianne Nielsine Skov; Mette Detlefsen; Henrik Hasman; Frank Møller Aarestrup; Rolf Sommer Kaas; Jesper Boye Nielsen; Henrik Westh; Hans Jørn Kolmos

doi:10.3201/eid2205.151835

Fatal Septicemia Linked to Transmission of MRSA Clonal Complex 398 in Hospital and Nursing Home, Denmark

Rikke Thoft Nielsen, Michael Kemp, Anette Holm, Marianne Nielsine Skov, Mette Detlefsen, Henrik Hasman, Frank Møller Aarestrup, Rolf Sommer Kaas, Jesper Boye Nielsen, Henrik Westh, Hans Jørn Kolmos

Department of Clinical Medicine

12 Citations (Scopus)

Abstract

We describe 2 fatal cases of methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 398 septicemia in persons who had no contact with livestock. Whole-genome sequencing of the isolated MRSA strains strongly suggest that both were of animal origin and that the patients had been infected through 2 independent person-to-person transmission chains.

Original language	English
Journal	Emerging Infectious Diseases
Volume	22
Issue number	5
Pages (from-to)	900-2
Number of pages	3
ISSN	1080-6040
DOIs	https://doi.org/10.3201/eid2205.151835
Publication status	Published - May 2016

Keywords

Aged
Animals
Cross Infection
Denmark
Farmers
Fatal Outcome
Female
Genome, Bacterial
Hospitals
Humans
Livestock
Male
Methicillin-Resistant Staphylococcus aureus
Middle Aged
Nursing Homes
Phylogeny
Renal Dialysis
Sepsis
Staphylococcal Infections
Case Reports
Journal Article

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title = "Fatal Septicemia Linked to Transmission of MRSA Clonal Complex 398 in Hospital and Nursing Home, Denmark",

abstract = "We describe 2 fatal cases of methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 398 septicemia in persons who had no contact with livestock. Whole-genome sequencing of the isolated MRSA strains strongly suggest that both were of animal origin and that the patients had been infected through 2 independent person-to-person transmission chains.",

keywords = "Aged, Animals, Cross Infection, Denmark, Farmers, Fatal Outcome, Female, Genome, Bacterial, Hospitals, Humans, Livestock, Male, Methicillin-Resistant Staphylococcus aureus, Middle Aged, Nursing Homes, Phylogeny, Renal Dialysis, Sepsis, Staphylococcal Infections, Case Reports, Journal Article",

author = "Nielsen, {Rikke Thoft} and Michael Kemp and Anette Holm and Skov, {Marianne Nielsine} and Mette Detlefsen and Henrik Hasman and Aarestrup, {Frank M{\o}ller} and Kaas, {Rolf Sommer} and Nielsen, {Jesper Boye} and Henrik Westh and Kolmos, {Hans J{\o}rn}",

year = "2016",

month = may,

doi = "10.3201/eid2205.151835",

language = "English",

volume = "22",

pages = "900--2",

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issn = "1080-6040",

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T1 - Fatal Septicemia Linked to Transmission of MRSA Clonal Complex 398 in Hospital and Nursing Home, Denmark

AU - Nielsen, Rikke Thoft

AU - Kemp, Michael

AU - Holm, Anette

AU - Skov, Marianne Nielsine

AU - Detlefsen, Mette

AU - Hasman, Henrik

AU - Aarestrup, Frank Møller

AU - Kaas, Rolf Sommer

AU - Nielsen, Jesper Boye

AU - Westh, Henrik

AU - Kolmos, Hans Jørn

PY - 2016/5

Y1 - 2016/5

N2 - We describe 2 fatal cases of methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 398 septicemia in persons who had no contact with livestock. Whole-genome sequencing of the isolated MRSA strains strongly suggest that both were of animal origin and that the patients had been infected through 2 independent person-to-person transmission chains.

AB - We describe 2 fatal cases of methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 398 septicemia in persons who had no contact with livestock. Whole-genome sequencing of the isolated MRSA strains strongly suggest that both were of animal origin and that the patients had been infected through 2 independent person-to-person transmission chains.

KW - Aged

KW - Animals

KW - Cross Infection

KW - Denmark

KW - Farmers

KW - Fatal Outcome

KW - Female

KW - Genome, Bacterial

KW - Hospitals

KW - Humans

KW - Livestock

KW - Male

KW - Methicillin-Resistant Staphylococcus aureus

KW - Middle Aged

KW - Nursing Homes

KW - Phylogeny

KW - Renal Dialysis

KW - Sepsis

KW - Staphylococcal Infections

KW - Case Reports

KW - Journal Article

U2 - 10.3201/eid2205.151835

DO - 10.3201/eid2205.151835

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C2 - 27089007

SN - 1080-6040

VL - 22

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EP - 902

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 5

ER -

Fatal Septicemia Linked to Transmission of MRSA Clonal Complex 398 in Hospital and Nursing Home, Denmark

Abstract

Keywords

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