Expression of inducible nitric oxide synthase and effects of L-arginine on colonic nitric oxide production and fluid transport in patients with "minimal colitis"

Anders Perner, Lars Andresen, Michel Normark, Birgit Fischer-Hansen, Jørgen Rask-Madsen

    4 Citations (Scopus)

    Abstract

    Some patients with idiopathic, chronic diarrhoea have minimal, non-specific colonic inflammation. As nitric oxide (NO) acts as a secretagogue in the colon, we studied the expression of inducible NO synthase (iNOS) in mucosal biopsies and the effects of NOS stimulation on colonic transfer of fluid and output of NO in patients with "minimal colitis".
    Original languageEnglish
    JournalScandinavian Journal of Gastroenterology
    Volume40
    Issue number9
    Pages (from-to)1042-8
    Number of pages7
    ISSN0036-5521
    DOIs
    Publication statusPublished - 2005

    Keywords

    • Adult
    • Arginine
    • Biological Markers
    • Biological Transport
    • Biopsy
    • Blotting, Western
    • Body Fluids
    • Colitis, Microscopic
    • Colonoscopy
    • Female
    • Follow-Up Studies
    • Humans
    • Immunohistochemistry
    • Intestinal Mucosa
    • Male
    • Middle Aged
    • Nitric Oxide
    • Nitric Oxide Synthase Type II
    • Perfusion

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