Experts do not agree when to treat retinopathy of prematurity based on plus disease

Carina Slidsborg; Julie Lyng Forman; Alistar Fielder; Sven Crafoord; Kirsten Lau Baggesen; Regitze Bangsgaard; Hans Callø Fledelius; Gorm Greisen; Morten la Cour

doi:10.1136/bjophthalmol-2011-300573

Experts do not agree when to treat retinopathy of prematurity based on plus disease

Carina Slidsborg, Julie Lyng Forman, Alistar Fielder, Sven Crafoord, Kirsten Lau Baggesen, Regitze Bangsgaard, Hans Callø Fledelius, Gorm Greisen, Morten la Cour

30 Citations (Scopus)

Abstract

ObjectivesTo investigate inter-reader agreement on five severity levels of central vascular changes (none, mild, moderate, severe pre-plus disease, plus disease) and aggressive posterior retinopathy of prematurity (ROP), and to see whether an unintended shift in indication for treatment occurred.MethodsFour international ROP readers participated. Before the grading of the photographs, the readers were informed that a high proportion of advanced ROP cases were included. In total, 243 photographs/948 quadrants were available from 136 infants. As a standard series of photographs was available, grading was performed under optimised conditions.ResultsThe four readers agreed on the quadrant scores of only 70 (7.38%) of the 948 quadrants-that is, on 1, 5, 15, 4 and 45 quadrants for scores 0, 1, 2, 3 and 4, respectively. The mean scores differed systematically between the readers (permutation test, p

Original language	English
Journal	British Journal of Ophthalmology
Volume	96
Issue number	4
Pages (from-to)	549-553
Number of pages	5
ISSN	0007-1161
DOIs	https://doi.org/10.1136/bjophthalmol-2011-300573
Publication status	Published - Apr 2012

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title = "Experts do not agree when to treat retinopathy of prematurity based on plus disease",

abstract = "ObjectivesTo investigate inter-reader agreement on five severity levels of central vascular changes (none, mild, moderate, severe pre-plus disease, plus disease) and aggressive posterior retinopathy of prematurity (ROP), and to see whether an unintended shift in indication for treatment occurred.MethodsFour international ROP readers participated. Before the grading of the photographs, the readers were informed that a high proportion of advanced ROP cases were included. In total, 243 photographs/948 quadrants were available from 136 infants. As a standard series of photographs was available, grading was performed under optimised conditions.ResultsThe four readers agreed on the quadrant scores of only 70 (7.38%) of the 948 quadrants-that is, on 1, 5, 15, 4 and 45 quadrants for scores 0, 1, 2, 3 and 4, respectively. The mean scores differed systematically between the readers (permutation test, p",

author = "Carina Slidsborg and Forman, {Julie Lyng} and Alistar Fielder and Sven Crafoord and Baggesen, {Kirsten Lau} and Regitze Bangsgaard and Fledelius, {Hans Call{\o}} and Gorm Greisen and {la Cour}, Morten",

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doi = "10.1136/bjophthalmol-2011-300573",

language = "English",

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T1 - Experts do not agree when to treat retinopathy of prematurity based on plus disease

AU - Slidsborg, Carina

AU - Forman, Julie Lyng

AU - Fielder, Alistar

AU - Crafoord, Sven

AU - Baggesen, Kirsten Lau

AU - Bangsgaard, Regitze

AU - Fledelius, Hans Callø

AU - Greisen, Gorm

AU - la Cour, Morten

PY - 2012/4

Y1 - 2012/4

N2 - ObjectivesTo investigate inter-reader agreement on five severity levels of central vascular changes (none, mild, moderate, severe pre-plus disease, plus disease) and aggressive posterior retinopathy of prematurity (ROP), and to see whether an unintended shift in indication for treatment occurred.MethodsFour international ROP readers participated. Before the grading of the photographs, the readers were informed that a high proportion of advanced ROP cases were included. In total, 243 photographs/948 quadrants were available from 136 infants. As a standard series of photographs was available, grading was performed under optimised conditions.ResultsThe four readers agreed on the quadrant scores of only 70 (7.38%) of the 948 quadrants-that is, on 1, 5, 15, 4 and 45 quadrants for scores 0, 1, 2, 3 and 4, respectively. The mean scores differed systematically between the readers (permutation test, p

AB - ObjectivesTo investigate inter-reader agreement on five severity levels of central vascular changes (none, mild, moderate, severe pre-plus disease, plus disease) and aggressive posterior retinopathy of prematurity (ROP), and to see whether an unintended shift in indication for treatment occurred.MethodsFour international ROP readers participated. Before the grading of the photographs, the readers were informed that a high proportion of advanced ROP cases were included. In total, 243 photographs/948 quadrants were available from 136 infants. As a standard series of photographs was available, grading was performed under optimised conditions.ResultsThe four readers agreed on the quadrant scores of only 70 (7.38%) of the 948 quadrants-that is, on 1, 5, 15, 4 and 45 quadrants for scores 0, 1, 2, 3 and 4, respectively. The mean scores differed systematically between the readers (permutation test, p

U2 - 10.1136/bjophthalmol-2011-300573

DO - 10.1136/bjophthalmol-2011-300573

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SP - 549

EP - 553

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

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ER -

Experts do not agree when to treat retinopathy of prematurity based on plus disease

Abstract

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