Expanding the optical trapping range of lipid vesicles to the nano-scale

Pól Martin Bendix; Lene Broeng Oddershede

doi:10.1021/nl203200g

Expanding the optical trapping range of lipid vesicles to the nano-scale

Pól Martin Bendix, Lene Broeng Oddershede

Biocomplexity

39 Citations (Scopus)

Abstract

Small unilamellar lipid vesicles with diameters down to 50 nm enclosing high refractive index sucrose cores can be optically trapped individually in three dimensions using a focused laser beam. Combined optical trapping and confocal microscopy allows for simultaneous quantitative measurements of the forces exerted on individual vesicles and of their size and shape. The position of individual vesicles in three dimensions is measured with nanometer spatial and ∼10 μs temporal resolution.

Original language	English
Journal	Nano Letters
Volume	11
Issue number	12
Pages (from-to)	5431–5437
Number of pages	7
ISSN	1530-6984
DOIs	https://doi.org/10.1021/nl203200g
Publication status	Published - 14 Dec 2011

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10.1021/nl203200g

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abstract = "Small unilamellar lipid vesicles with diameters down to 50 nm enclosing high refractive index sucrose cores can be optically trapped individually in three dimensions using a focused laser beam. Combined optical trapping and confocal microscopy allows for simultaneous quantitative measurements of the forces exerted on individual vesicles and of their size and shape. The position of individual vesicles in three dimensions is measured with nanometer spatial and ∼10 μs temporal resolution.",

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AU - Oddershede, Lene Broeng

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AB - Small unilamellar lipid vesicles with diameters down to 50 nm enclosing high refractive index sucrose cores can be optically trapped individually in three dimensions using a focused laser beam. Combined optical trapping and confocal microscopy allows for simultaneous quantitative measurements of the forces exerted on individual vesicles and of their size and shape. The position of individual vesicles in three dimensions is measured with nanometer spatial and ∼10 μs temporal resolution.

U2 - 10.1021/nl203200g

DO - 10.1021/nl203200g

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JO - Nano Letters

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Expanding the optical trapping range of lipid vesicles to the nano-scale

Abstract

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