TY - JOUR
T1 - ESMO Consensus Conference on malignant lymphoma
T2 - General perspectives and recommendations for the clinical management of the elderly patient with malignant lymphoma
AU - Buske, C.
AU - Hutchings, M.
AU - Ladetto, M.
AU - Goede, V.
AU - Mey, U.
AU - Soubeyran, P.
AU - Spina, M.
AU - Stauder, R.
AU - Trněný, M.
AU - Wedding, U.
AU - Fields, P.
AU - Dreyling, Martin
AU - Ferreri, Andrés J.M.
AU - Gaidano, Gianluca
AU - Le Gouill, Steven
AU - Luminari, Stefano
AU - de Nully Brown, Peter
AU - Pfreundschuh, Michael
AU - Pott, Christiane
AU - Schmitz, Norbert
AU - Balari, Anna Sureda
AU - van Imhoff, Gustaaf
AU - Walewski, Jan
AU - Zamò, Alberto
AU - Zucca, Emanuele
AU - The ESMO Lymphoma Consensus Conference Panel Members
PY - 2018
Y1 - 2018
N2 - The European Society for Medical Oncology (ESMO) consensus conference on mature B cell lymphomas and chronic lymphocytic leukaemia (CLL) was held on 20 June 2015 in Lugano, Switzerland, and included a multidisciplinary panel of 25 leading experts. The aimof the conference was to develop recommendations on critical subjects difficult to consider in detail in the ESMO Clinical Practice Guidelines. The following areas were identified: (1) the elderly patient, (2) prognostic factors suitable for clinical use, and (3) the 'ultra-high-risk' group. Before the conference, the expert panel was divided into three working groups; each group focused on one of these areas in order to address clinically-relevant questions relating to that topic. All relevant scientific literature, as identified by the experts, was reviewed in advance. During the consensus conference, each working group developed recommendations to address each of the four questions assigned to their group. These recommendations were presented to the entire panel and a consensus was reached. This consensus, which was further developed in continuous post-meeting discussions, formed the basis of three manuscripts, each covering one of the three key areas identified. This manuscript presents the consensus recommendations regarding the clinical management of elderly patients diagnosed with malignant lymphoma. Four clinically-relevant topics identified by the panel were: 1) how to define patient fitness, 2) assessing quality of life, 3) diagnostic work-up and 4) clinical management of elderly patients with lymphoma. Each of these key topics is addressed in the context of five different lymphoma entities, namely: CLL, follicular lymphoma, mantle cell lymphoma, peripheral T-cell lymphoma and diffuse large B-cell lymphoma. Results, including a summary of evidence supporting each recommendation, are detailed in thismanuscript.
AB - The European Society for Medical Oncology (ESMO) consensus conference on mature B cell lymphomas and chronic lymphocytic leukaemia (CLL) was held on 20 June 2015 in Lugano, Switzerland, and included a multidisciplinary panel of 25 leading experts. The aimof the conference was to develop recommendations on critical subjects difficult to consider in detail in the ESMO Clinical Practice Guidelines. The following areas were identified: (1) the elderly patient, (2) prognostic factors suitable for clinical use, and (3) the 'ultra-high-risk' group. Before the conference, the expert panel was divided into three working groups; each group focused on one of these areas in order to address clinically-relevant questions relating to that topic. All relevant scientific literature, as identified by the experts, was reviewed in advance. During the consensus conference, each working group developed recommendations to address each of the four questions assigned to their group. These recommendations were presented to the entire panel and a consensus was reached. This consensus, which was further developed in continuous post-meeting discussions, formed the basis of three manuscripts, each covering one of the three key areas identified. This manuscript presents the consensus recommendations regarding the clinical management of elderly patients diagnosed with malignant lymphoma. Four clinically-relevant topics identified by the panel were: 1) how to define patient fitness, 2) assessing quality of life, 3) diagnostic work-up and 4) clinical management of elderly patients with lymphoma. Each of these key topics is addressed in the context of five different lymphoma entities, namely: CLL, follicular lymphoma, mantle cell lymphoma, peripheral T-cell lymphoma and diffuse large B-cell lymphoma. Results, including a summary of evidence supporting each recommendation, are detailed in thismanuscript.
KW - Consensus
KW - Diagnosis
KW - Elderly patient
KW - Lymphoma
KW - Quality of life
KW - Treatment
U2 - 10.1093/annonc/mdx413
DO - 10.1093/annonc/mdx413
M3 - Journal article
C2 - 29194473
AN - SCOPUS:85046069858
SN - 0923-7534
VL - 29
SP - 544
EP - 562
JO - Annals of Oncology
JF - Annals of Oncology
IS - 3
ER -