Environmental exposure assessment in European birth cohorts: results from the ENRIECO project

Ulrike Gehring; Maribel Casas; Bert Brunekreef; Anna Bergström; Jens Peter Bonde; Jérémie Botton; Cecile Chévrier; Sylvaine Cordier; Joachim Heinrich; Cynthia Hohmann; Thomas Keil; Jordi Sunyer; Christina G Tischer; Gunnar Toft; Magnus Wickman; Martine Vrijheid; Mark Nieuwenhuijsen

doi:10.1186/1476-069X-12-8

Environmental exposure assessment in European birth cohorts: results from the ENRIECO project

Ulrike Gehring, Maribel Casas, Bert Brunekreef, Anna Bergström, Jens Peter Bonde, Jérémie Botton, Cecile Chévrier, Sylvaine Cordier, Joachim Heinrich, Cynthia Hohmann, Thomas Keil, Jordi Sunyer, Christina G Tischer, Gunnar Toft, Magnus Wickman, Martine Vrijheid, Mark Nieuwenhuijsen

Department of Public Health

30 Citations (Scopus)

Abstract

Environmental exposures during pregnancy and early life may have adverse health effects. Single birth cohort studies often lack statistical power to tease out such effects reliably. To improve the use of existing data and to facilitate collaboration among these studies, an inventory of the environmental exposure and health data in these studies was made as part of the ENRIECO (Environmental Health Risks in European Birth Cohorts) project. The focus with regard to exposure was on outdoor air pollution, water contamination, allergens and biological organisms, metals, pesticides, smoking and second hand tobacco smoke (SHS), persistent organic pollutants (POPs), noise, radiation, and occupational exposures. The review lists methods and data on environmental exposures in 37 European birth cohort studies. Most data is currently available for smoking and SHS (N=37 cohorts), occupational exposures (N=33), outdoor air pollution, and allergens and microbial agents (N=27). Exposure modeling is increasingly used for long-term air pollution exposure assessment; biomonitoring is used for assessment of exposure to metals, POPs and other chemicals; and environmental monitoring for house dust mite exposure assessment. Collaborative analyses with data from several birth cohorts have already been performed successfully for outdoor air pollution, water contamination, allergens, biological contaminants, molds, POPs and SHS. Key success factors for collaborative analyses are common definitions of main exposure and health variables. Our review emphasizes that such common definitions need ideally be arrived at in the study design phase. However, careful comparison of methods used in existing studies also offers excellent opportunities for collaborative analyses. Investigators can use this review to evaluate the potential for future collaborative analyses with respect to data availability and methods used in the different cohorts and to identify potential partners for a specific research question.

Original language	English
Article number	8
Journal	Environmental Health
Volume	12
Number of pages	14
ISSN	1476-069X
DOIs	https://doi.org/10.1186/1476-069X-12-8
Publication status	Published - 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1186/1476-069X-12-8

Cite this

Gehring, U., Casas, M., Brunekreef, B., Bergström, A., Bonde, J. P., Botton, J., Chévrier, C., Cordier, S., Heinrich, J., Hohmann, C., Keil, T., Sunyer, J., Tischer, C. G., Toft, G., Wickman, M., Vrijheid, M., & Nieuwenhuijsen, M. (2013). Environmental exposure assessment in European birth cohorts: results from the ENRIECO project. Environmental Health, 12, [8]. https://doi.org/10.1186/1476-069X-12-8

Gehring, U, Casas, M, Brunekreef, B, Bergström, A, Bonde, JP, Botton, J, Chévrier, C, Cordier, S, Heinrich, J, Hohmann, C, Keil, T, Sunyer, J, Tischer, CG, Toft, G, Wickman, M, Vrijheid, M & Nieuwenhuijsen, M 2013, 'Environmental exposure assessment in European birth cohorts: results from the ENRIECO project', Environmental Health, vol. 12, 8. https://doi.org/10.1186/1476-069X-12-8

@article{a315d06f91d740ff90dc46b103169587,

title = "Environmental exposure assessment in European birth cohorts: results from the ENRIECO project",

abstract = "Environmental exposures during pregnancy and early life may have adverse health effects. Single birth cohort studies often lack statistical power to tease out such effects reliably. To improve the use of existing data and to facilitate collaboration among these studies, an inventory of the environmental exposure and health data in these studies was made as part of the ENRIECO (Environmental Health Risks in European Birth Cohorts) project. The focus with regard to exposure was on outdoor air pollution, water contamination, allergens and biological organisms, metals, pesticides, smoking and second hand tobacco smoke (SHS), persistent organic pollutants (POPs), noise, radiation, and occupational exposures. The review lists methods and data on environmental exposures in 37 European birth cohort studies. Most data is currently available for smoking and SHS (N=37 cohorts), occupational exposures (N=33), outdoor air pollution, and allergens and microbial agents (N=27). Exposure modeling is increasingly used for long-term air pollution exposure assessment; biomonitoring is used for assessment of exposure to metals, POPs and other chemicals; and environmental monitoring for house dust mite exposure assessment. Collaborative analyses with data from several birth cohorts have already been performed successfully for outdoor air pollution, water contamination, allergens, biological contaminants, molds, POPs and SHS. Key success factors for collaborative analyses are common definitions of main exposure and health variables. Our review emphasizes that such common definitions need ideally be arrived at in the study design phase. However, careful comparison of methods used in existing studies also offers excellent opportunities for collaborative analyses. Investigators can use this review to evaluate the potential for future collaborative analyses with respect to data availability and methods used in the different cohorts and to identify potential partners for a specific research question.",

author = "Ulrike Gehring and Maribel Casas and Bert Brunekreef and Anna Bergstr{\"o}m and Bonde, {Jens Peter} and J{\'e}r{\'e}mie Botton and Cecile Ch{\'e}vrier and Sylvaine Cordier and Joachim Heinrich and Cynthia Hohmann and Thomas Keil and Jordi Sunyer and Tischer, {Christina G} and Gunnar Toft and Magnus Wickman and Martine Vrijheid and Mark Nieuwenhuijsen",

year = "2013",

doi = "10.1186/1476-069X-12-8",

language = "English",

volume = "12",

journal = "Environmental Health",

issn = "1476-069X",

publisher = "BioMed Central Ltd.",

}

TY - JOUR

T1 - Environmental exposure assessment in European birth cohorts

T2 - results from the ENRIECO project

AU - Gehring, Ulrike

AU - Casas, Maribel

AU - Brunekreef, Bert

AU - Bergström, Anna

AU - Bonde, Jens Peter

AU - Botton, Jérémie

AU - Chévrier, Cecile

AU - Cordier, Sylvaine

AU - Heinrich, Joachim

AU - Hohmann, Cynthia

AU - Keil, Thomas

AU - Sunyer, Jordi

AU - Tischer, Christina G

AU - Toft, Gunnar

AU - Wickman, Magnus

AU - Vrijheid, Martine

AU - Nieuwenhuijsen, Mark

PY - 2013

Y1 - 2013

N2 - Environmental exposures during pregnancy and early life may have adverse health effects. Single birth cohort studies often lack statistical power to tease out such effects reliably. To improve the use of existing data and to facilitate collaboration among these studies, an inventory of the environmental exposure and health data in these studies was made as part of the ENRIECO (Environmental Health Risks in European Birth Cohorts) project. The focus with regard to exposure was on outdoor air pollution, water contamination, allergens and biological organisms, metals, pesticides, smoking and second hand tobacco smoke (SHS), persistent organic pollutants (POPs), noise, radiation, and occupational exposures. The review lists methods and data on environmental exposures in 37 European birth cohort studies. Most data is currently available for smoking and SHS (N=37 cohorts), occupational exposures (N=33), outdoor air pollution, and allergens and microbial agents (N=27). Exposure modeling is increasingly used for long-term air pollution exposure assessment; biomonitoring is used for assessment of exposure to metals, POPs and other chemicals; and environmental monitoring for house dust mite exposure assessment. Collaborative analyses with data from several birth cohorts have already been performed successfully for outdoor air pollution, water contamination, allergens, biological contaminants, molds, POPs and SHS. Key success factors for collaborative analyses are common definitions of main exposure and health variables. Our review emphasizes that such common definitions need ideally be arrived at in the study design phase. However, careful comparison of methods used in existing studies also offers excellent opportunities for collaborative analyses. Investigators can use this review to evaluate the potential for future collaborative analyses with respect to data availability and methods used in the different cohorts and to identify potential partners for a specific research question.

AB - Environmental exposures during pregnancy and early life may have adverse health effects. Single birth cohort studies often lack statistical power to tease out such effects reliably. To improve the use of existing data and to facilitate collaboration among these studies, an inventory of the environmental exposure and health data in these studies was made as part of the ENRIECO (Environmental Health Risks in European Birth Cohorts) project. The focus with regard to exposure was on outdoor air pollution, water contamination, allergens and biological organisms, metals, pesticides, smoking and second hand tobacco smoke (SHS), persistent organic pollutants (POPs), noise, radiation, and occupational exposures. The review lists methods and data on environmental exposures in 37 European birth cohort studies. Most data is currently available for smoking and SHS (N=37 cohorts), occupational exposures (N=33), outdoor air pollution, and allergens and microbial agents (N=27). Exposure modeling is increasingly used for long-term air pollution exposure assessment; biomonitoring is used for assessment of exposure to metals, POPs and other chemicals; and environmental monitoring for house dust mite exposure assessment. Collaborative analyses with data from several birth cohorts have already been performed successfully for outdoor air pollution, water contamination, allergens, biological contaminants, molds, POPs and SHS. Key success factors for collaborative analyses are common definitions of main exposure and health variables. Our review emphasizes that such common definitions need ideally be arrived at in the study design phase. However, careful comparison of methods used in existing studies also offers excellent opportunities for collaborative analyses. Investigators can use this review to evaluate the potential for future collaborative analyses with respect to data availability and methods used in the different cohorts and to identify potential partners for a specific research question.

U2 - 10.1186/1476-069X-12-8

DO - 10.1186/1476-069X-12-8

M3 - Journal article

SN - 1476-069X

VL - 12

JO - Environmental Health

JF - Environmental Health

M1 - 8

ER -

Environmental exposure assessment in European birth cohorts: results from the ENRIECO project

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this