Endothelial cell loss and refractive predictability in femtosecond laser-assisted cataract surgery compared with conventional cataract surgery

Therese Krarup; Lars Morten Holm; Morten la Cour; Hadi Kjaerbo

doi:10.1111/aos.12406

Endothelial cell loss and refractive predictability in femtosecond laser-assisted cataract surgery compared with conventional cataract surgery

Therese Krarup, Lars Morten Holm, Morten la Cour, Hadi Kjaerbo

Department of Clinical Medicine

45 Citations (Scopus)

Abstract

Purpose To investigate the amount of endothelial cell loss (ECL) and refractive predictability by femtosecond laser-assisted cataract surgery (FLACS) compared to conventional phacoemulsification cataract surgery (CPS). Methods Forty-seven patients had one eye operated by FLACS and the contralateral eye operated by CPS (stop and chop technique). Both eyes had intraocular aspheric lenses implanted. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), central corneal endothelial cell count and hexagonality with a non-contact specular microscope were assessed preoperatively, 1-3 days postoperatively and 3 months postoperatively. Results Three days postoperatively, mean ECL was 249 cells/mm² (SD ± 744) (9.1%) by FLACS and 235 cells/mm² (SD ± 681) (8.2%) by CPS (p = 0.87). Three months postoperatively, mean ECL was 274 cells/mm² (SD ± 358) (11.4%) by FLACS compared with 333 cells/mm² (SD ± 422) (13.9%) by CPS, (p = 0.30) 3 months postoperatively, hexagonality was decreased by 1.8% (SD ± 30) by FLACS and by 1.4% (SD ± 13) by CPS, (p = 0.84). The mean absolute difference from the attempted refraction was 0.37 dioptres (D) (SD ± 0.33) by FLACS and 0.41 D (SD ± 0.42) by CPS (p = 0.56). Mean CDVA was 0.89 (0.3; 1.25) by FLACS and 0.93 (0.4; 1.25) by CPS at 3 months postoperatively (p = 0.36). Within both groups, 70% gained a CDVA of 6/6. Mean surgery time was 9.3 min (SD ± 1.9) by FLACS and 8.0 min (SD ± 1.9) by CPS, (p = 0.0018). Mean phaco energy was 3.78 U/S (SD ± 5.1) and 5.45 U/S (SD ± 4.6) (p < 0.0001) by FLACS and CPS, respectively. Conclusion We found no significant difference in ECL and refractive predictability between FLACS and CPS 3 months postoperatively.

Original language	English
Journal	Acta Ophthalmologica
Volume	92
Issue number	7
Pages (from-to)	617-622
Number of pages	6
ISSN	1755-375X
DOIs	https://doi.org/10.1111/aos.12406
Publication status	Published - 1 Nov 2014

Keywords

Adult
Cataract Extraction
Cell Count
Corneal Endothelial Cell Loss
Endothelium, Corneal
Humans
Laser Therapy
Lens Implantation, Intraocular
Phacoemulsification
Prospective Studies
Refractive Errors
Visual Acuity

Access to Document

10.1111/aos.12406

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/aos.12406

Cite this

@article{4e77811f96bc4bd2ac3767d657210e88,

title = "Endothelial cell loss and refractive predictability in femtosecond laser-assisted cataract surgery compared with conventional cataract surgery",

abstract = "Purpose To investigate the amount of endothelial cell loss (ECL) and refractive predictability by femtosecond laser-assisted cataract surgery (FLACS) compared to conventional phacoemulsification cataract surgery (CPS). Methods Forty-seven patients had one eye operated by FLACS and the contralateral eye operated by CPS (stop and chop technique). Both eyes had intraocular aspheric lenses implanted. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), central corneal endothelial cell count and hexagonality with a non-contact specular microscope were assessed preoperatively, 1-3 days postoperatively and 3 months postoperatively. Results Three days postoperatively, mean ECL was 249 cells/mm2 (SD ± 744) (9.1%) by FLACS and 235 cells/mm2 (SD ± 681) (8.2%) by CPS (p = 0.87). Three months postoperatively, mean ECL was 274 cells/mm2 (SD ± 358) (11.4%) by FLACS compared with 333 cells/mm2 (SD ± 422) (13.9%) by CPS, (p = 0.30) 3 months postoperatively, hexagonality was decreased by 1.8% (SD ± 30) by FLACS and by 1.4% (SD ± 13) by CPS, (p = 0.84). The mean absolute difference from the attempted refraction was 0.37 dioptres (D) (SD ± 0.33) by FLACS and 0.41 D (SD ± 0.42) by CPS (p = 0.56). Mean CDVA was 0.89 (0.3; 1.25) by FLACS and 0.93 (0.4; 1.25) by CPS at 3 months postoperatively (p = 0.36). Within both groups, 70% gained a CDVA of 6/6. Mean surgery time was 9.3 min (SD ± 1.9) by FLACS and 8.0 min (SD ± 1.9) by CPS, (p = 0.0018). Mean phaco energy was 3.78 U/S (SD ± 5.1) and 5.45 U/S (SD ± 4.6) (p < 0.0001) by FLACS and CPS, respectively. Conclusion We found no significant difference in ECL and refractive predictability between FLACS and CPS 3 months postoperatively.",

keywords = "Adult, Cataract Extraction, Cell Count, Corneal Endothelial Cell Loss, Endothelium, Corneal, Humans, Laser Therapy, Lens Implantation, Intraocular, Phacoemulsification, Prospective Studies, Refractive Errors, Visual Acuity",

author = "Therese Krarup and Holm, {Lars Morten} and {la Cour}, Morten and Hadi Kjaerbo",

note = "{\textcopyright} 2014 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.",

year = "2014",

month = nov,

day = "1",

doi = "10.1111/aos.12406",

language = "English",

volume = "92",

pages = "617--622",

journal = "Acta Ophthalmologica",

issn = "1755-375X",

publisher = "Wiley-Blackwell",

number = "7",

}

TY - JOUR

T1 - Endothelial cell loss and refractive predictability in femtosecond laser-assisted cataract surgery compared with conventional cataract surgery

AU - Krarup, Therese

AU - Holm, Lars Morten

AU - la Cour, Morten

AU - Kjaerbo, Hadi

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Purpose To investigate the amount of endothelial cell loss (ECL) and refractive predictability by femtosecond laser-assisted cataract surgery (FLACS) compared to conventional phacoemulsification cataract surgery (CPS). Methods Forty-seven patients had one eye operated by FLACS and the contralateral eye operated by CPS (stop and chop technique). Both eyes had intraocular aspheric lenses implanted. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), central corneal endothelial cell count and hexagonality with a non-contact specular microscope were assessed preoperatively, 1-3 days postoperatively and 3 months postoperatively. Results Three days postoperatively, mean ECL was 249 cells/mm2 (SD ± 744) (9.1%) by FLACS and 235 cells/mm2 (SD ± 681) (8.2%) by CPS (p = 0.87). Three months postoperatively, mean ECL was 274 cells/mm2 (SD ± 358) (11.4%) by FLACS compared with 333 cells/mm2 (SD ± 422) (13.9%) by CPS, (p = 0.30) 3 months postoperatively, hexagonality was decreased by 1.8% (SD ± 30) by FLACS and by 1.4% (SD ± 13) by CPS, (p = 0.84). The mean absolute difference from the attempted refraction was 0.37 dioptres (D) (SD ± 0.33) by FLACS and 0.41 D (SD ± 0.42) by CPS (p = 0.56). Mean CDVA was 0.89 (0.3; 1.25) by FLACS and 0.93 (0.4; 1.25) by CPS at 3 months postoperatively (p = 0.36). Within both groups, 70% gained a CDVA of 6/6. Mean surgery time was 9.3 min (SD ± 1.9) by FLACS and 8.0 min (SD ± 1.9) by CPS, (p = 0.0018). Mean phaco energy was 3.78 U/S (SD ± 5.1) and 5.45 U/S (SD ± 4.6) (p < 0.0001) by FLACS and CPS, respectively. Conclusion We found no significant difference in ECL and refractive predictability between FLACS and CPS 3 months postoperatively.

AB - Purpose To investigate the amount of endothelial cell loss (ECL) and refractive predictability by femtosecond laser-assisted cataract surgery (FLACS) compared to conventional phacoemulsification cataract surgery (CPS). Methods Forty-seven patients had one eye operated by FLACS and the contralateral eye operated by CPS (stop and chop technique). Both eyes had intraocular aspheric lenses implanted. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), central corneal endothelial cell count and hexagonality with a non-contact specular microscope were assessed preoperatively, 1-3 days postoperatively and 3 months postoperatively. Results Three days postoperatively, mean ECL was 249 cells/mm2 (SD ± 744) (9.1%) by FLACS and 235 cells/mm2 (SD ± 681) (8.2%) by CPS (p = 0.87). Three months postoperatively, mean ECL was 274 cells/mm2 (SD ± 358) (11.4%) by FLACS compared with 333 cells/mm2 (SD ± 422) (13.9%) by CPS, (p = 0.30) 3 months postoperatively, hexagonality was decreased by 1.8% (SD ± 30) by FLACS and by 1.4% (SD ± 13) by CPS, (p = 0.84). The mean absolute difference from the attempted refraction was 0.37 dioptres (D) (SD ± 0.33) by FLACS and 0.41 D (SD ± 0.42) by CPS (p = 0.56). Mean CDVA was 0.89 (0.3; 1.25) by FLACS and 0.93 (0.4; 1.25) by CPS at 3 months postoperatively (p = 0.36). Within both groups, 70% gained a CDVA of 6/6. Mean surgery time was 9.3 min (SD ± 1.9) by FLACS and 8.0 min (SD ± 1.9) by CPS, (p = 0.0018). Mean phaco energy was 3.78 U/S (SD ± 5.1) and 5.45 U/S (SD ± 4.6) (p < 0.0001) by FLACS and CPS, respectively. Conclusion We found no significant difference in ECL and refractive predictability between FLACS and CPS 3 months postoperatively.

KW - Adult

KW - Cataract Extraction

KW - Cell Count

KW - Corneal Endothelial Cell Loss

KW - Endothelium, Corneal

KW - Humans

KW - Laser Therapy

KW - Lens Implantation, Intraocular

KW - Phacoemulsification

KW - Prospective Studies

KW - Refractive Errors

KW - Visual Acuity

U2 - 10.1111/aos.12406

DO - 10.1111/aos.12406

M3 - Journal article

C2 - 24888390

SN - 1755-375X

VL - 92

SP - 617

EP - 622

JO - Acta Ophthalmologica

JF - Acta Ophthalmologica

IS - 7

ER -

Endothelial cell loss and refractive predictability in femtosecond laser-assisted cataract surgery compared with conventional cataract surgery

Abstract

Keywords

Access to Document

Fingerprint

Cite this