Abstract
Human leptospirosis is a zoonotic disease of global importance that causes significant morbidity and mortality, particularly in developing nations. In this review, the history, epidemiology, transmission, clinical presentation and treatment of this disease, and its impact in Australia, are discussed. Central to this review is the delineation of diagnostic methods for the disease and the challenges that this disease presents for both the clinician and diagnostic laboratory. This information should furnish clinicians with an updated tool to help overcome a number of problems associated with the diagnosis of leptospirosis.
Original language | English |
---|---|
Journal | Pathogens and Global Health |
Volume | 104 |
Issue number | 7 |
Pages (from-to) | 543-56 |
Number of pages | 14 |
ISSN | 2047-7724 |
DOIs | |
Publication status | Published - 1 Oct 2010 |
Keywords
- Anti-Bacterial Agents
- Antibodies, Bacterial
- Australia
- Biological Markers
- Communicable Diseases, Emerging
- Enzyme-Linked Immunosorbent Assay
- Humans
- Leptospira
- Leptospirosis
- Polymerase Chain Reaction