Effects of hyperventilation and hypocapnic/normocapnic hypoxemia on renal function and lithium clearance in humans

H Christensen; T Klausen; N Fogh-Andersen; I Plum; I L Kanstrup; J M Hansen; Niels Vidiendal Olsen

Effects of hyperventilation and hypocapnic/normocapnic hypoxemia on renal function and lithium clearance in humans

H Christensen, T Klausen, N Fogh-Andersen, I Plum, I L Kanstrup, J M Hansen, Niels Vidiendal Olsen

14 Citations (Scopus)

Abstract

Using the renal clearance of lithium as an index of proximal tubular outflow, this study tested the hypothesis that acute hypocapnic hypoxemia decreases proximal tubular reabsorption to the same extent as hypocapnic normoxemia (hyperventilation) and that this response is blunted during normocapnic hypoxemia.

Original language	English
Journal	Anesthesiology
Volume	89
Issue number	6
Pages (from-to)	1389-400
Number of pages	12
ISSN	0003-3022
Publication status	Published - Dec 1998

Keywords

Adult
Anoxia
Blood Gas Analysis
Carbon Dioxide
Hemodynamics
Hormones
Humans
Hyperventilation
Hypocapnia
Kidney
Kidney Function Tests
Kidney Tubules, Proximal
Lithium
Male
Respiratory Function Tests

Cite this

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title = "Effects of hyperventilation and hypocapnic/normocapnic hypoxemia on renal function and lithium clearance in humans",

abstract = "Using the renal clearance of lithium as an index of proximal tubular outflow, this study tested the hypothesis that acute hypocapnic hypoxemia decreases proximal tubular reabsorption to the same extent as hypocapnic normoxemia (hyperventilation) and that this response is blunted during normocapnic hypoxemia.",

keywords = "Adult, Anoxia, Blood Gas Analysis, Carbon Dioxide, Hemodynamics, Hormones, Humans, Hyperventilation, Hypocapnia, Kidney, Kidney Function Tests, Kidney Tubules, Proximal, Lithium, Male, Respiratory Function Tests",

author = "H Christensen and T Klausen and N Fogh-Andersen and I Plum and Kanstrup, {I L} and Hansen, {J M} and Olsen, {Niels Vidiendal}",

year = "1998",

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T1 - Effects of hyperventilation and hypocapnic/normocapnic hypoxemia on renal function and lithium clearance in humans

AU - Christensen, H

AU - Klausen, T

AU - Fogh-Andersen, N

AU - Plum, I

AU - Kanstrup, I L

AU - Hansen, J M

AU - Olsen, Niels Vidiendal

PY - 1998/12

Y1 - 1998/12

N2 - Using the renal clearance of lithium as an index of proximal tubular outflow, this study tested the hypothesis that acute hypocapnic hypoxemia decreases proximal tubular reabsorption to the same extent as hypocapnic normoxemia (hyperventilation) and that this response is blunted during normocapnic hypoxemia.

AB - Using the renal clearance of lithium as an index of proximal tubular outflow, this study tested the hypothesis that acute hypocapnic hypoxemia decreases proximal tubular reabsorption to the same extent as hypocapnic normoxemia (hyperventilation) and that this response is blunted during normocapnic hypoxemia.

KW - Adult

KW - Anoxia

KW - Blood Gas Analysis

KW - Carbon Dioxide

KW - Hemodynamics

KW - Hormones

KW - Humans

KW - Hyperventilation

KW - Hypocapnia

KW - Kidney

KW - Kidney Function Tests

KW - Kidney Tubules, Proximal

KW - Lithium

KW - Male

KW - Respiratory Function Tests

M3 - Journal article

C2 - 9856713

SN - 0003-3022

VL - 89

SP - 1389

EP - 1400

JO - Anesthesiology

JF - Anesthesiology

IS - 6

ER -

Effects of hyperventilation and hypocapnic/normocapnic hypoxemia on renal function and lithium clearance in humans

Abstract

Keywords

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