Abstract
The objective of this study was to determine the effects of mega-doses of vitamin C (0.3, 0.6 and 0.9% of diet) as a dietary supplement for rats on selected indices of the antioxidative/oxidative state in 40 growing Wistar rats (4x10). It was found that L-ascorbic acid and Total Antioxidative State (TAS) in plasma did not increase with increasing vitamin C supply. The results indicate that high doses of L-ascorbic acid (0.3 and 0.9 but not 0.6%) increased the concentration of this antioxidant in plasma. Supplementation of vitamin C above 0.3% to the diets had pro-oxidative effects on lipid structures, while application of 0.9% promoted oxidative degradation of rat livers.
| Original language | English |
|---|---|
| Journal | Journal of Animal and Feed Sciences |
| Volume | 14 |
| Issue number | Suppl.1 |
| Pages (from-to) | 553-556 |
| Number of pages | 4 |
| ISSN | 1230-1388 |
| Publication status | Published - 2005 |
Keywords
- Former LIFE faculty
- ascorbic acid
- antioxidative/oxidative state
- rats