Abstract
The effect of a putative Na/H exchange inhibition on histamine and [C]arachidonic acid ([C]AA) release has been examined in rat peritoneal mast cells, using either addition of amiloride or removal of extracellular Na. The cells were stimulated by non-immunological agents, i.e. calcium ionophore A23187, nerve growth factor (NGF), thapsigargin and compound 48/80. On the basis of the results obtained, a possible role for Na/H exchange in rat mast cell secretion is discussed.
| Original language | English |
|---|---|
| Journal | Agents and Actions |
| Volume | 27 |
| Issue number | 1-2 |
| Pages (from-to) | 39-42 |
| Number of pages | 4 |
| ISSN | 0065-4299 |
| Publication status | Published - 1 Jan 1989 |