EBV-associated gastric carcinoma in high- and low-incidence areas for nasopharyngeal carcinoma

TY - JOUR

T1 - EBV-associated gastric carcinoma in high- and low-incidence areas for nasopharyngeal carcinoma

AU - Boysen, T.

AU - Mohammadi, M.

AU - Melbye, M.

AU - Hamilton-Dutoit, S.

AU - Vainer, B.

AU - Hansen, A.V.

AU - Wohlfahrt, J.

AU - Friborg, J.

N1 - Keywords: Adult; Aged; Case-Control Studies; Female; Herpesvirus 4, Human; Humans; Incidence; Male; Middle Aged; Nasopharyngeal Neoplasms; Stomach Neoplasms

PY - 2009

Y1 - 2009

N2 - BACKGROUND: Approximately 10% of gastric carcinomas are associated with Epstein-Barr virus (EBV). The Inuit in Greenland have a high incidence of EBV-associated nasopharyngeal carcinoma. METHODS: We conducted a population-based case-control study comparing gastric carcinomas in Greenland and in Denmark. RESULTS: The prevalence rate of EBV-associated gastric carcinomas was 8.5% in both populations. CONCLUSION: The findings of this study argue against a general susceptibility to EBV-associated carcinomas among the Inuit.

AB - BACKGROUND: Approximately 10% of gastric carcinomas are associated with Epstein-Barr virus (EBV). The Inuit in Greenland have a high incidence of EBV-associated nasopharyngeal carcinoma. METHODS: We conducted a population-based case-control study comparing gastric carcinomas in Greenland and in Denmark. RESULTS: The prevalence rate of EBV-associated gastric carcinomas was 8.5% in both populations. CONCLUSION: The findings of this study argue against a general susceptibility to EBV-associated carcinomas among the Inuit.

U2 - 10.1038/sj.bjc.6605168

DO - 10.1038/sj.bjc.6605168

M3 - Journal article

C2 - 19603026

SN - 0007-0920

VL - 101

SP - 530

EP - 533

JO - The British journal of cancer. Supplement

JF - The British journal of cancer. Supplement

IS - 3

ER -