Downstream targets of WRKY33

Klaus Petersen; Berthe Katrine Fiil; John Mundy; Morten Petersen

Downstream targets of WRKY33

Klaus Petersen, Berthe Katrine Fiil, John Mundy, Morten Petersen

14 Citations (Scopus)

Abstract

Innate immunity signaling pathways in both animals and plants are regulated by mitogen-activated protein kinase (MAPK) cascades. In a recent publication we show that MPK4 and its substrate MKS1 interact with WRKY33 in vivo, and that WRKY33 is released from complexes with MPK4 upon infection. Transcriptome analysis of a wrky33 loss-of-function mutant identified a subset of defense-related genes as putative targets of WRKY33. These genes include PAD3 and CYP71A13, which encode cytochrome P450 monoxygenases required for synthesis of the antimicrobial phytoalexin camalexin. Chromatin immunoprecipitation confirmed that WRKY33 bound the promoter of PAD3 when plants were inoculated with pathogens. Here we further discuss the involvement of two other targets of WRKY33, NUDT6 and ROF2 in defense responses against invading pathogens.

Original language	English
Journal	Plant Signalling & Behavior
Volume	3
Issue number	11
Pages (from-to)	1033-1034
ISSN	1559-2316
Publication status	Published - 2008

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title = "Downstream targets of WRKY33",

abstract = "Innate immunity signaling pathways in both animals and plants are regulated by mitogen-activated protein kinase (MAPK) cascades. In a recent publication we show that MPK4 and its substrate MKS1 interact with WRKY33 in vivo, and that WRKY33 is released from complexes with MPK4 upon infection. Transcriptome analysis of a wrky33 loss-of-function mutant identified a subset of defense-related genes as putative targets of WRKY33. These genes include PAD3 and CYP71A13, which encode cytochrome P450 monoxygenases required for synthesis of the antimicrobial phytoalexin camalexin. Chromatin immunoprecipitation confirmed that WRKY33 bound the promoter of PAD3 when plants were inoculated with pathogens. Here we further discuss the involvement of two other targets of WRKY33, NUDT6 and ROF2 in defense responses against invading pathogens.",

author = "Klaus Petersen and Fiil, {Berthe Katrine} and John Mundy and Morten Petersen",

note = "Key words: Arabidopsis, MAPK cascade, defense response, transcription factor, target gene",

year = "2008",

language = "English",

volume = "3",

pages = "1033--1034",

journal = "Plant Signalling & Behavior",

issn = "1559-2316",

publisher = "Taylor & Francis",

number = "11",

}

TY - JOUR

T1 - Downstream targets of WRKY33

AU - Petersen, Klaus

AU - Fiil, Berthe Katrine

AU - Mundy, John

AU - Petersen, Morten

N1 - Key words: Arabidopsis, MAPK cascade, defense response, transcription factor, target gene

PY - 2008

Y1 - 2008

N2 - Innate immunity signaling pathways in both animals and plants are regulated by mitogen-activated protein kinase (MAPK) cascades. In a recent publication we show that MPK4 and its substrate MKS1 interact with WRKY33 in vivo, and that WRKY33 is released from complexes with MPK4 upon infection. Transcriptome analysis of a wrky33 loss-of-function mutant identified a subset of defense-related genes as putative targets of WRKY33. These genes include PAD3 and CYP71A13, which encode cytochrome P450 monoxygenases required for synthesis of the antimicrobial phytoalexin camalexin. Chromatin immunoprecipitation confirmed that WRKY33 bound the promoter of PAD3 when plants were inoculated with pathogens. Here we further discuss the involvement of two other targets of WRKY33, NUDT6 and ROF2 in defense responses against invading pathogens.

AB - Innate immunity signaling pathways in both animals and plants are regulated by mitogen-activated protein kinase (MAPK) cascades. In a recent publication we show that MPK4 and its substrate MKS1 interact with WRKY33 in vivo, and that WRKY33 is released from complexes with MPK4 upon infection. Transcriptome analysis of a wrky33 loss-of-function mutant identified a subset of defense-related genes as putative targets of WRKY33. These genes include PAD3 and CYP71A13, which encode cytochrome P450 monoxygenases required for synthesis of the antimicrobial phytoalexin camalexin. Chromatin immunoprecipitation confirmed that WRKY33 bound the promoter of PAD3 when plants were inoculated with pathogens. Here we further discuss the involvement of two other targets of WRKY33, NUDT6 and ROF2 in defense responses against invading pathogens.

M3 - Journal article

SN - 1559-2316

VL - 3

SP - 1033

EP - 1034

JO - Plant Signalling & Behavior

JF - Plant Signalling & Behavior

IS - 11

ER -

Downstream targets of WRKY33

Abstract

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