Dopamine natriuresis in salt-repleted, water-loaded humans: a dose-response study

Niels Vidiendal Olsen, M H Olsen, J Bonde, I L Kanstrup, I Plum, S Strandgaard, P P Leyssac

21 Citations (Scopus)

Abstract

The purpose of the present study was to define the dose-response relationship between exogenous dopamine and systemic haemodynamics, renal haemodynamics, and renal excretory function at infusion rates in the range 0 to 12.5 microg kg(-1) min(-1) in normal volunteers.
Original languageEnglish
JournalBritish Journal of Clinical Pharmacology
Volume43
Issue number5
Pages (from-to)509-20
Number of pages12
ISSN0306-5251
Publication statusPublished - May 1997

Keywords

  • Adult
  • Aldosterone
  • Body Water
  • Catecholamines
  • Dopamine
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Electrolytes
  • Glomerular Filtration Rate
  • Hemodynamics
  • Humans
  • Lithium
  • Male
  • Natriuresis
  • Reference Values
  • Renal Circulation
  • Renin
  • Vascular Resistance

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