Abstract
BACKGROUND: The risk of donor-transmitted cancer is evident.
CASE REPORT: We report the case of a 69-year-old woman who was transplanted with a kidney from a deceased donor. Four days after transplantation a routine ultrasound scan revealed a 3-cm tumor in the middle-upper pole of the allograft. A biopsy showed the tumor to be papillary renal cell carcinoma. The patient was treated with radiofrequency ablation. This procedure was complicated by the development of a cutaneous fistula and open surgery was done with resection of an area of necrosis in the kidney and of the fistula. The maintenance immunosuppressive regimen was modified with a change in treatment to everolimus in combination with reduced dose mycophenolate and low-dose steroids. The patient was followed for 4.5 years and during that time she remained dialysis independent with an excellent allograft function (serum creatinine, 95 μmol/L [1.04 mg/dL]).
CONCLUSIONS: To the best of our knowledge, this is the first case in which a donor-transmitted tumor was diagnosed in the renal allograft only 4 days after transplantation and subsequently treated successfully with radiofrequency ablation.
| Original language | English |
|---|---|
| Journal | Transplantation Proceedings |
| Volume | 47 |
| Issue number | 10 |
| Pages (from-to) | 3031-3 |
| Number of pages | 3 |
| ISSN | 0041-1345 |
| DOIs | |
| Publication status | Published - 1 Dec 2015 |
